α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling

BACKGROUND: Excessive osteoclast activation is an important cause of imbalanced bone remodeling that leads to pathological bone destruction. This is a clear feature of many osteolytic diseases such as rheumatoid arthritis, osteoporosis, and osteolysis around prostheses. Because many natural compound...

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Detalles Bibliográficos
Autores principales: Zhang, Wenkan, Jiang, Guangyao, Zhou, Xiaozhong, Huang, Leyi, Meng, Jiahong, He, Bin, Qi, Yiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898470/
https://www.ncbi.nlm.nih.gov/pubmed/35248101
http://dx.doi.org/10.1186/s13020-022-00589-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898470/
https://www.ncbi.nlm.nih.gov/pubmed/35248101
http://dx.doi.org/10.1186/s13020-022-00589-5

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