Cargando…

α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling

BACKGROUND: Excessive osteoclast activation is an important cause of imbalanced bone remodeling that leads to pathological bone destruction. This is a clear feature of many osteolytic diseases such as rheumatoid arthritis, osteoporosis, and osteolysis around prostheses. Because many natural compound...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wenkan, Jiang, Guangyao, Zhou, Xiaozhong, Huang, Leyi, Meng, Jiahong, He, Bin, Qi, Yiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898470/ https://www.ncbi.nlm.nih.gov/pubmed/35248101 http://dx.doi.org/10.1186/s13020-022-00589-5

Ejemplares similares

Stachydrine prevents LPS‐induced bone loss by inhibiting osteoclastogenesis via NF‐κB and Akt signalling
por: Meng, Jiahong, et al.
Publicado: (2019)

Artemether attenuates LPS-induced inflammatory bone loss by inhibiting osteoclastogenesis and bone resorption via suppression of MAPK signaling pathway
por: Wu, Haobo, et al.
Publicado: (2018)

Palmitoleic Acid Inhibits RANKL-Induced Osteoclastogenesis and Bone Resorption by Suppressing NF-κB and MAPK Signalling Pathways
por: van Heerden, Bernadette, et al.
Publicado: (2017)

Intrinsic Restriction of TNF-Mediated Inflammatory Osteoclastogenesis and Bone Resorption
por: Zhao, Baohong
Publicado: (2020)

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways
por: Hu, Xuantao, et al.
Publicado: (2020)

IL-33 Inhibits TNF-α-Induced Osteoclastogenesis and Bone Resorption
por: Ohori, Fumitoshi, et al.
Publicado: (2020)

Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
por: Quan, Gui-Hua, et al.
Publicado: (2015)

Regulation of Osteoclastogenesis and Bone Resorption by miRNAs
por: Inoue, Kazuki, et al.
Publicado: (2021)

Effects of O‐methylated (−)‐epigallocatechin gallate (EGCG) on LPS‐induced osteoclastogenesis, bone resorption, and alveolar bone loss in mice
por: Tominari, Tsukasa, et al.
Publicado: (2017)

Zoledronic acid inhibits osteoclastogenesis and bone resorptive function by suppressing RANKL-mediated NF-κB and JNK and their downstream signalling pathways
por: Huang, Xiao-Lin, et al.
Publicado: (2022)

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis
por: Braun, Tobias, et al.
Publicado: (2011)

Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation
por: Guo, Wen, et al.
Publicado: (2021)

Protective Effects of Punicalagin on Osteoporosis by Inhibiting Osteoclastogenesis and Inflammation via the NF-κB and MAPK Pathways
por: Wang, Wei, et al.
Publicado: (2020)

Galangin suppresses RANKL‐induced osteoclastogenesis via inhibiting MAPK and NF‐κB signalling pathways
por: Li, Xiucheng, et al.
Publicado: (2021)

NF-κB-Mediated Regulation of Osteoclastogenesis
por: Boyce, Brendan F., et al.
Publicado: (2015)

Ginsenoside Rb3 Inhibits Pro-Inflammatory Cytokines via MAPK/AKT/NF-κB Pathways and Attenuates Rat Alveolar Bone Resorption in Response to Porphyromonas gingivalis LPS
por: Sun, Minmin, et al.
Publicado: (2020)

C-phycocyanin attenuates RANKL-induced osteoclastogenesis and bone resorption in vitro through inhibiting ROS levels, NFATc1 and NF-κB activation
por: AlQranei, Mohammed S., et al.
Publicado: (2020)

Aminothiazoles inhibit osteoclastogenesis and PGE (2) production in LPS‐stimulated co‐cultures of periodontal ligament and RAW 264.7 cells, and RANKL‐mediated osteoclastogenesis and bone resorption in PBMCs
por: Kats, Anna, et al.
Publicado: (2018)

Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors
por: Zhao, Baohong, et al.
Publicado: (2011)

Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo
por: Estell, Eben G, et al.
Publicado: (2020)

Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity
por: Lee, Jin-Young, et al.
Publicado: (2021)

Nepetin inhibits osteoclastogenesis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signalling pathway, and autophagy
por: Chu, Binxiang, et al.
Publicado: (2020)

GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways
por: Tang, Chen-Yi, et al.
Publicado: (2022)

FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF-κB and HDAC4/ATF Pathways
por: Chen, Chongwei, et al.
Publicado: (2023)

LPS- and LTA-Induced Expression of IL-6 and TNF-α in Neonatal and Adult Blood: Role of MAPKs and NF-κB
por: Koch, Lutz, et al.
Publicado: (2014)

Sesamolin Protects Mice From Ovariectomized Bone Loss by Inhibiting Osteoclastogenesis and RANKL-Mediated NF-κB and MAPK Signaling Pathways
por: Yang, Xue, et al.
Publicado: (2021)

Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells
por: Zeng, Yan-Ping, et al.
Publicado: (2016)

Deacylcynaropicrin Inhibits RANKL-Induced Osteoclastogenesis by Inhibiting NF-κB and MAPK and Promoting M2 Polarization of Macrophages
por: Li, Zhikun, et al.
Publicado: (2019)

Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways
por: Zhi, Xin, et al.
Publicado: (2020)

Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways
por: Shen, Bingyu, et al.
Publicado: (2023)

TNF-α and RANKL promote osteoclastogenesis by upregulating RANK via the NF-κB pathway
por: Luo, Gang, et al.
Publicado: (2018)

Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption
por: Shang, Nan, et al.
Publicado: (2019)

LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption
por: Zhang, Ruilin, et al.
Publicado: (2020)

Marein Prevented LPS-Induced Osteoclastogenesis by Regulating the NF-κB Pathway In Vitro
por: Li, Yuling, et al.
Publicado: (2022)

Azilsartan inhibits inflammation-triggered bone resorption and osteoclastogenesis in vivo via suppression of TNF-α expression in macrophages
por: Fan, Ziqiu, et al.
Publicado: (2023)

Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-κB Signaling Pathway
por: Oliveira, Tatiane, et al.
Publicado: (2015)

Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis
por: Lee, Won-Seok, et al.
Publicado: (2018)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Anti-inflammation of isoliquiritigenin via the inhibition of NF-κB and MAPK in LPS-stimulated MAC-T cells
por: Li, Manman, et al.
Publicado: (2022)

Astragalus polysaccharide attenuates LPS‐related inflammatory osteolysis by suppressing osteoclastogenesis by reducing the MAPK signalling pathway
por: Yang, Jianye, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ld90emmevfhiahibgq8c5q5a9l