A CFH peptide-decorated liposomal oxymatrine inactivates cancer-associated fibroblasts of hepatocellular carcinoma through epithelial–mesenchymal transition reversion

Cancer-associated fibroblasts (CAFs) deteriorate tumor microenvironment (TME) and hinder intra-tumoral drug delivery. Direct depleting CAFs exists unpredictable risks of tumor metastasis. Epithelial–mesenchymal transition (EMT) is a critical process of CAFs converted from hepatic stellate cells duri...

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Detalles Bibliográficos
Autores principales: Guo, Jian, Zeng, Huating, Shi, Xinmeng, Han, Tao, Liu, Yimin, Liu, Yuping, Liu, Congyan, Qu, Ding, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898522/
https://www.ncbi.nlm.nih.gov/pubmed/35248071
http://dx.doi.org/10.1186/s12951-022-01311-1

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