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Non-inferiority test for a continuous variable with a flexible margin in an active controlled trial: an application to the “Stratall ANRS 12110 / ESTHER” trial

BACKGROUND: Non-inferiority trials are becoming increasingly popular in public health and clinical research. The choice of the non-inferiority margin is the cornerstone of such trials. Most of the time, the non-inferiority margin is fixed and constant, determined from historical trials as a fraction...

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Detalles Bibliográficos
Autores principales: Sandie, Arsene Brunelle, Molinari, Nicolas, Wanjoya, Anthony, Kouanfack, Charles, Laurent, Christian, Tchatchueng-Mbougua, Jules Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898539/
https://www.ncbi.nlm.nih.gov/pubmed/35248123
http://dx.doi.org/10.1186/s13063-022-06118-x