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Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients
PURPOSE: The aim of this study was to evaluate the safety and feasibility of applying enhanced recovery after surgery (ERAS) protocol in elderly colorectal cancer patients. METHODS: The medical records of patients who underwent elective colorectal cancer surgery at our institution, from January 2017...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Coloproctology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898633/ https://www.ncbi.nlm.nih.gov/pubmed/34284558 http://dx.doi.org/10.3393/ac.2021.00283.0040 |
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author | Koh, Wooree Lee, Chul Seung Bae, Jung Hoon Al-Sawat, Abdullah Lee, In Kyu Jin, Hyeong Yong |
author_facet | Koh, Wooree Lee, Chul Seung Bae, Jung Hoon Al-Sawat, Abdullah Lee, In Kyu Jin, Hyeong Yong |
author_sort | Koh, Wooree |
collection | PubMed |
description | PURPOSE: The aim of this study was to evaluate the safety and feasibility of applying enhanced recovery after surgery (ERAS) protocol in elderly colorectal cancer patients. METHODS: The medical records of patients who underwent elective colorectal cancer surgery at our institution, from January 2017 to December 2017, were reviewed. Patients were divided into 2 groups: the young group (YG, patients aged 70 and under 70 years) and the old group (OG, patients over 70 years old). Perioperative outcomes and length of hospital stay were compared between both groups. RESULTS: In total, 335 patients were enrolled; 237 were YG and 98 were OG. Despite the poorer baseline characteristics of OG, the perioperative outcomes were similar. Length of hospital stay was not different between the groups (YG, 5 days vs. OG, 5 days; P=0.320). When comparing the postoperative complications using the comprehensive complication index (CCI), there was no significant difference (YG, 8.0±13.2 vs. OG, 11.7±23.0; P=0.130). In regression analysis, old age (>70 years) was not a risk factor for high CCI in all patients. In multivariate analysis, C-reactive protein (CRP) level on postoperative day (POD) 3 to 4 was the only strong predictive factor for high CCI in elderly patients. CONCLUSION: Implementing the ERAS protocol in patients aged >70 years is safe and feasible. High CRP (≥6.47 mg/dL) on POD 3 to 4 can be used as a safety index to postpone discharge in elderly patients. |
format | Online Article Text |
id | pubmed-8898633 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Korean Society of Coloproctology |
record_format | MEDLINE/PubMed |
spelling | pubmed-88986332022-03-11 Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients Koh, Wooree Lee, Chul Seung Bae, Jung Hoon Al-Sawat, Abdullah Lee, In Kyu Jin, Hyeong Yong Ann Coloproctol Original Article PURPOSE: The aim of this study was to evaluate the safety and feasibility of applying enhanced recovery after surgery (ERAS) protocol in elderly colorectal cancer patients. METHODS: The medical records of patients who underwent elective colorectal cancer surgery at our institution, from January 2017 to December 2017, were reviewed. Patients were divided into 2 groups: the young group (YG, patients aged 70 and under 70 years) and the old group (OG, patients over 70 years old). Perioperative outcomes and length of hospital stay were compared between both groups. RESULTS: In total, 335 patients were enrolled; 237 were YG and 98 were OG. Despite the poorer baseline characteristics of OG, the perioperative outcomes were similar. Length of hospital stay was not different between the groups (YG, 5 days vs. OG, 5 days; P=0.320). When comparing the postoperative complications using the comprehensive complication index (CCI), there was no significant difference (YG, 8.0±13.2 vs. OG, 11.7±23.0; P=0.130). In regression analysis, old age (>70 years) was not a risk factor for high CCI in all patients. In multivariate analysis, C-reactive protein (CRP) level on postoperative day (POD) 3 to 4 was the only strong predictive factor for high CCI in elderly patients. CONCLUSION: Implementing the ERAS protocol in patients aged >70 years is safe and feasible. High CRP (≥6.47 mg/dL) on POD 3 to 4 can be used as a safety index to postpone discharge in elderly patients. Korean Society of Coloproctology 2022-02 2021-07-21 /pmc/articles/PMC8898633/ /pubmed/34284558 http://dx.doi.org/10.3393/ac.2021.00283.0040 Text en Copyright © 2022 The Korean Society of Coloproctology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Koh, Wooree Lee, Chul Seung Bae, Jung Hoon Al-Sawat, Abdullah Lee, In Kyu Jin, Hyeong Yong Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients |
title | Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients |
title_full | Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients |
title_fullStr | Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients |
title_full_unstemmed | Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients |
title_short | Clinical validation of implementing Enhanced Recovery After Surgery protocol in elderly colorectal cancer patients |
title_sort | clinical validation of implementing enhanced recovery after surgery protocol in elderly colorectal cancer patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898633/ https://www.ncbi.nlm.nih.gov/pubmed/34284558 http://dx.doi.org/10.3393/ac.2021.00283.0040 |
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