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Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study

BACKGROUND: The goals of glycemic management for patients with diabetes are to prevent or delay complications and optimize quality of life. However, in clinical practice, the recommended glycemic control target is difficult to achieve. Therefore, it is important to identify factors that influence th...

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Autores principales: Abera, Rodas Getachew, Demesse, Eyouel Shimeles, Boko, Wako Dedecha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898656/
https://www.ncbi.nlm.nih.gov/pubmed/35249547
http://dx.doi.org/10.1186/s12902-022-00974-z
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author Abera, Rodas Getachew
Demesse, Eyouel Shimeles
Boko, Wako Dedecha
author_facet Abera, Rodas Getachew
Demesse, Eyouel Shimeles
Boko, Wako Dedecha
author_sort Abera, Rodas Getachew
collection PubMed
description BACKGROUND: The goals of glycemic management for patients with diabetes are to prevent or delay complications and optimize quality of life. However, in clinical practice, the recommended glycemic control target is difficult to achieve. Therefore, it is important to identify factors that influence the outcomes of glycemia to improve the quality of diabetic management. The study aimed to evaluate the level and factors associated with glycemic control among type 2 diabetic outpatients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. METHODS: A hospital-based cross-sectional study was conducted among systematically selected 325 patients with type 2 diabetes who attended diabetic clinics at Tikur Anbessa Specialized Hospital. Pretested, structured, and interviewer-administered questionnaires were used to collect sociodemographic and diabetes-related information from March 1 to May 30, 2021. HbA1c was used to assess glycemic control according to the HbA1c target of < 7% (‘good’ control) as recommended by the American Diabetes Association for non-pregnant adults. The HbA1c level in the range of 7–8% was defined as ‘inadequate’ control and ‘poor’ at levels > 8%. Data entry and analysis were performed using SPSS v26. Multivariate logistic regression analysis was used to identify determinants of glycemic control. RESULTS: The median level of HbA1c of the participants was 8.4% (IQR 6.8–10.1). And approximately three-quarters (73.8%) of the patients had inadequate and poor glycemic control (HbA1c ≥ 7%). Older age (AOR: 2.46, 95% CI: 1.28–6.01), DM duration of > 10 years (AOR: 3.15, 95% CI: 2.22–6.54), insulin therapy (AOR: 3.07, 95% CI: 2.10–6.12), poor diet compliance (AOR: 1.97, 95% CI: 1.28–3.52) and failure to set goals for glycemic control (AOR: 3.42, 95% CI: 2.17–5.97) were factors associated with inadequate and poor glycemic control. CONCLUSIONS: The study revealed that a significant number of diabetic patients had inadequate and poor glycemic control levels. And this was associated with older age, longer duration of DM, insulin therapy, poor diet compliance, and failure to set control goals. This requires a focus on the associated factors identified and tailored management mechanisms to maintain good glycemic control. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12902-022-00974-z.
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spelling pubmed-88986562022-03-07 Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study Abera, Rodas Getachew Demesse, Eyouel Shimeles Boko, Wako Dedecha BMC Endocr Disord Research BACKGROUND: The goals of glycemic management for patients with diabetes are to prevent or delay complications and optimize quality of life. However, in clinical practice, the recommended glycemic control target is difficult to achieve. Therefore, it is important to identify factors that influence the outcomes of glycemia to improve the quality of diabetic management. The study aimed to evaluate the level and factors associated with glycemic control among type 2 diabetic outpatients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. METHODS: A hospital-based cross-sectional study was conducted among systematically selected 325 patients with type 2 diabetes who attended diabetic clinics at Tikur Anbessa Specialized Hospital. Pretested, structured, and interviewer-administered questionnaires were used to collect sociodemographic and diabetes-related information from March 1 to May 30, 2021. HbA1c was used to assess glycemic control according to the HbA1c target of < 7% (‘good’ control) as recommended by the American Diabetes Association for non-pregnant adults. The HbA1c level in the range of 7–8% was defined as ‘inadequate’ control and ‘poor’ at levels > 8%. Data entry and analysis were performed using SPSS v26. Multivariate logistic regression analysis was used to identify determinants of glycemic control. RESULTS: The median level of HbA1c of the participants was 8.4% (IQR 6.8–10.1). And approximately three-quarters (73.8%) of the patients had inadequate and poor glycemic control (HbA1c ≥ 7%). Older age (AOR: 2.46, 95% CI: 1.28–6.01), DM duration of > 10 years (AOR: 3.15, 95% CI: 2.22–6.54), insulin therapy (AOR: 3.07, 95% CI: 2.10–6.12), poor diet compliance (AOR: 1.97, 95% CI: 1.28–3.52) and failure to set goals for glycemic control (AOR: 3.42, 95% CI: 2.17–5.97) were factors associated with inadequate and poor glycemic control. CONCLUSIONS: The study revealed that a significant number of diabetic patients had inadequate and poor glycemic control levels. And this was associated with older age, longer duration of DM, insulin therapy, poor diet compliance, and failure to set control goals. This requires a focus on the associated factors identified and tailored management mechanisms to maintain good glycemic control. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12902-022-00974-z. BioMed Central 2022-03-07 /pmc/articles/PMC8898656/ /pubmed/35249547 http://dx.doi.org/10.1186/s12902-022-00974-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Abera, Rodas Getachew
Demesse, Eyouel Shimeles
Boko, Wako Dedecha
Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
title Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
title_full Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
title_fullStr Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
title_full_unstemmed Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
title_short Evaluation of glycemic control and related factors among outpatients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
title_sort evaluation of glycemic control and related factors among outpatients with type 2 diabetes at tikur anbessa specialized hospital, addis ababa, ethiopia: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898656/
https://www.ncbi.nlm.nih.gov/pubmed/35249547
http://dx.doi.org/10.1186/s12902-022-00974-z
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