Squalene synthase predicts poor prognosis in stage I‐III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression

Colon adenocarcinoma (COAD) is one of the most prevalent malignancies, with poor prognosis and lack of effective treatment targets. Squalene synthase (FDFT1) is an upstream enzyme of squalene epoxidase (SQLE) in cholesterol biosynthesis. In a previous study, we revealed that SQLE promotes colon canc...

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Detalles Bibliográficos
Autores principales: Jiang, Huihong, Tang, Erjiang, Chen, Ying, Liu, Hailong, Zhao, Yun, Lin, Moubin, He, Luwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898704/
https://www.ncbi.nlm.nih.gov/pubmed/34939274
http://dx.doi.org/10.1111/cas.15248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898704/
https://www.ncbi.nlm.nih.gov/pubmed/34939274
http://dx.doi.org/10.1111/cas.15248

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