High prevalence of TERT aberrations in myxoid liposarcoma: TERT reactivation may play a crucial role in tumorigenesis

Myxoid liposarcoma (MLPS) is genetically characterized by FUS‐DDIT3 or EWSR1‐DDIT3 gene fusion and the high frequency of hotspot mutations (C228T or C250T) in the promoter region of telomerase reverse transcriptase (TERT) that encodes the TERT protein. The latter leads to telomerase reactivation, a...

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Detalles Bibliográficos
Autores principales: Kunieda, Junko, Yamashita, Kyoko, Togashi, Yuki, Baba, Satoko, Sakata, Seiji, Inamura, Kentaro, Ae, Keisuke, Matsumoto, Seiichi, Machinami, Rikuo, Kitagawa, Masanobu, Takeuchi, Kengo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898734/
https://www.ncbi.nlm.nih.gov/pubmed/34971481
http://dx.doi.org/10.1111/cas.15256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898734/
https://www.ncbi.nlm.nih.gov/pubmed/34971481
http://dx.doi.org/10.1111/cas.15256

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