Cargando…

CXCR4 promotes the growth and metastasis of esophageal squamous cell carcinoma as a critical downstream mediator of HIF‐1α

C–X–C motif chemokine receptor 4 (CXCR4) belongs to the CXC chemokine receptor family, which mediates the metastasis of tumor cells and promotes the malignant development of cancers. However, its biological role and regulatory mechanism in esophageal squamous cell carcinoma (ESCC) remain unclear. He...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Xianxian, Zhang, Hongdian, Sui, Zhilin, Gao, Yongyin, Gong, Lei, Chen, Chuangui, Ma, Zhao, Tang, Peng, Yu, Zhentao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898735/ https://www.ncbi.nlm.nih.gov/pubmed/34990040 http://dx.doi.org/10.1111/cas.15265

Ejemplares similares

The biological role of the CXCL12/CXCR4 axis in esophageal squamous cell carcinoma
por: Wu, Xianxian, et al.
Publicado: (2021)

USP4 promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting TAK1
por: Zhang, Hongdian, et al.
Publicado: (2023)

Establishment of a risk model by integrating hypoxia genes in predicting prognosis of esophageal squamous cell carcinoma
por: Xiao, Wanyi, et al.
Publicado: (2022)

Krüppel-Like Factor 4 Enhances Sensitivity of Cisplatin to Esophageal Squamous Cell Carcinoma (ESCC) Cells
por: Chen, Chuangui, et al.
Publicado: (2017)

High expression of PPFIA1 in human esophageal squamous cell carcinoma correlates with tumor metastasis and poor prognosis
por: Gao, Yongyin, et al.
Publicado: (2023)

Development of a novel biomarker model for predicting preoperative lymph node metastatic extent in esophageal squamous cell carcinoma(1)
por: Ma, Zhao, et al.
Publicado: (2017)

Integrated Analysis of lncRNA–Mediated ceRNA Network in Lung Adenocarcinoma
por: Wu, Xianxian, et al.
Publicado: (2020)

Characterization of the Immune Cell Infiltration Landscape in Esophageal Squamous Cell Carcinoma
por: Sui, Zhilin, et al.
Publicado: (2022)

Identification and Validation of Immune-Related Gene Signature for Predicting Lymph Node Metastasis and Prognosis in Lung Adenocarcinoma
por: Jia, Ran, et al.
Publicado: (2021)

Metastatic lymph node ratio demonstrates better prognostic stratification than pN staging in patients with esophageal squamous cell carcinoma after esophagectomy
por: Zhang, Hongdian, et al.
Publicado: (2016)

Does tumor size improve the accuracy of prognostic prediction in patients with esophageal squamous cell carcinoma after surgical resection?
por: Zhang, Hongdian, et al.
Publicado: (2016)

High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma
por: Ren, Peng, et al.
Publicado: (2017)

A nomogram to predict lymph node metastasis risk for early esophageal squamous cell carcinoma
por: Duan, Xiaofeng, et al.
Publicado: (2021)

Lymph node ratio-based staging system as an alternative to the current TNM staging system to assess outcome in adenocarcinoma of the esophagogastric junction after surgical resection
por: Zhang, Hongdian, et al.
Publicado: (2016)

HIF-1α Promotes the Metastasis of Esophageal Squamous Cell Carcinoma by Targeting SP1
por: Hu, Xueting, et al.
Publicado: (2020)

Metastasis patterns and prognosis in breast cancer patients aged ≥ 80 years: a SEER database analysis
por: Han, Youming, et al.
Publicado: (2021)

Prognostic Significance of the Combination of Fibrinogen and Tumor Marker Index in Esophageal Squamous Cell Carcinoma Patients
por: Qiao, Yufeng, et al.
Publicado: (2021)

ASAP3 is a downstream target of HIF-1α and is critical for progression of lung adenocarcinoma
por: Zhang, Pingping, et al.
Publicado: (2019)

Prognostic Significance of the Preoperative Albumin/Fibrinogen Ratio in Patients with Esophageal Squamous Cell Carcinoma after Surgical Resection
por: Zhang, Hongdian, et al.
Publicado: (2021)

Comparison of clinicopathological features and prognostic significance between synchronous multiple primary and solitary esophageal squamous cell carcinomas
por: Yang, Yueyang, et al.
Publicado: (2022)

Circ_0058063 upregulates GLUT1 expression and promotes glucose-uptake in esophageal squamous-cell carcinomas
por: Zheng, Yinbin, et al.
Publicado: (2020)

Myeloid-Derived Suppressor Cells in Immune Microenvironment Promote Progression of Esophagogastric Junction Adenocarcinoma
por: Wang, Ying, et al.
Publicado: (2021)

Lymph node dissection around left recurrent laryngeal nerve: robot-assisted vs. video-assisted McKeown esophagectomy for esophageal squamous cell carcinoma
por: Duan, Xiaofeng, et al.
Publicado: (2020)

HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis
por: Huang, Rui, et al.
Publicado: (2017)

Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma
por: Wang, Ni, et al.
Publicado: (2013)

Prognostic significance of the epithelial-mesenchymal transition factor zinc finger E-box-binding homeobox 2 in esophageal squamous cell carcinoma
por: Huo, Xiaodong, et al.
Publicado: (2017)

The prognostic performance of the log odds of positive lymph nodes in patients with esophageal squamous cell carcinoma: A population study of the US SEER database and a Chinese single‐institution cohort
por: Zhang, Hongdian, et al.
Publicado: (2021)

Risk factors for lymph node metastasis of the left recurrent laryngeal nerve in patients with esophageal squamous cell carcinoma
por: Chen, Chuangui, et al.
Publicado: (2021)

Comparison of the therapeutic effects of endoscopic submucosal dissection and minimally invasive esophagectomy for T1 stage esophageal carcinoma
por: Gong, Lei, et al.
Publicado: (2019)

CypA, a Gene Downstream of HIF-1α, Promotes the Development of PDAC
por: Zhang, Huan, et al.
Publicado: (2014)

A feed-forward loop between nuclear translocation of CXCR4 and HIF-1α promotes renal cell carcinoma metastasis
por: Bao, Yi, et al.
Publicado: (2018)

Expression of chemokine receptor CXCR4 in esophageal squamous cell and adenocarcinoma
por: Gockel, Ines, et al.
Publicado: (2006)

Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer
por: Wu, Yugang, et al.
Publicado: (2010)

Development and validation of nodal staging score in pN0 patients with esophageal squamous cell carcinoma: A population study from the SEER database and a single‐institution cohort
por: Wang, Haitong, et al.
Publicado: (2022)

Comparison of lymph node metastasis pattern from esophagogastric junction adenocarcinoma versus very low thoracic esophageal squamous cancer: a propensity-matched analysis
por: Ma, Zhao, et al.
Publicado: (2023)

PDGF-BB is involved in HIF-1α/CXCR4/CXCR7 axis promoting capillarization of hepatic sinusoidal endothelial cells
por: Fang, Jing, et al.
Publicado: (2022)

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
por: Frost, Julianty, et al.
Publicado: (2016)

Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets
por: van Gisbergen, Marike W., et al.
Publicado: (2020)

ATF5 and HIF1α cooperatively activate HIF1 signaling pathway in esophageal cancer
por: He, Feng, et al.
Publicado: (2021)

α-Enolase Lies Downstream of mTOR/HIF1α and Promotes Thyroid Carcinoma Progression by Regulating CST1
por: Liu, Yang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m4e3j3bm1ii396g1fhho2697gm