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Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting

Eliciting antibodies to surface-exposed viral glycoproteins can generate protective responses that control and prevent future infections. Targeting conserved sites may reduce the likelihood of viral escape and limit the spread of related viruses with pandemic potential. Here we leverage rational imm...

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Detalles Bibliográficos
Autores principales:	Hauser, Blake M., Sangesland, Maya, St. Denis, Kerri J., Lam, Evan C., Case, James Brett, Windsor, Ian W., Feldman, Jared, Caradonna, Timothy M., Kannegieter, Ty, Diamond, Michael S., Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898741/ https://www.ncbi.nlm.nih.gov/pubmed/35303475 http://dx.doi.org/10.1016/j.celrep.2022.110561

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