Boosting antitumor response with PSMA-targeted immunomodulatory VLPs, harboring costimulatory TNFSF ligands and GM-CSF cytokine

Therapeutic strategies based on immunomodulation have improved cancer therapy. Most approaches target co-stimulatory pathways or the inhibition of immunosuppressive mechanisms, to enhance immune response and overcome the immune tolerance of tumors. Here, we propose a novel platform to deliver target...

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Detalles Bibliográficos
Autores principales: Palameta, Soledad, Manrique-Rincón, Andrea J., Toscaro, Jessica M., Semionatto, Isadora F., Fonseca, Matheus C., Rosa, Rhubia S.M., Ruas, Luciana P., Oliveira, Paulo S.L., Bajgelman, Marcio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898762/
https://www.ncbi.nlm.nih.gov/pubmed/35284623
http://dx.doi.org/10.1016/j.omto.2022.02.010

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