Cargando…

Using Network Pharmacology to Systematically Decipher the Potential Mechanisms of Jisuikang in the Treatment of Spinal Cord Injury

OBJECTIVE: To identify the potential pharmacological targets of Jisuikang (JSK) for the treatment of spinal cord injury (SCI) using network pharmacology. METHODS: The bioactive compounds of JSK herbs and their corresponding potential SCI targets were obtained from three traditional Chinese medicine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shaoshuo, Shao, Yang, Chen, Hao, Wang, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898796/ https://www.ncbi.nlm.nih.gov/pubmed/35265147 http://dx.doi.org/10.1155/2022/4932153

Ejemplares similares

Jisuikang Promotes the Repair of Spinal Cord Injury in Rats by Regulating NgR/RhoA/ROCK Signal Pathway
por: Wu, Chengjie, et al.
Publicado: (2020)

Deciphering Pharmacological Mechanism of Buyang Huanwu Decoction for Spinal Cord Injury by Network Pharmacology Approach
por: Xiong, Zhencheng, et al.
Publicado: (2021)

Jisuikang, a Chinese herbal formula, increases neurotrophic factor expression and promotes the recovery of neurological function after spinal cord injury
por: Guo, Yang, et al.
Publicado: (2017)

Deciphering the protective effect of Buzhong Yiqi Decoction on osteoporotic fracture through network pharmacology and experimental validation
por: Hua, Zhen, et al.
Publicado: (2023)

Systematically Investigating the Pharmacological Mechanism of Momordica grosvenori in the Treatment of Spinal Cord Injury by Network Pharmacology and Experimental Verification
por: Wang, Jiling, et al.
Publicado: (2023)

Systematically Deciphering the Pharmacological Mechanism of Fructus Aurantii via Network Pharmacology
por: Jin, Qionglong, et al.
Publicado: (2021)

Deciphering glial scar after spinal cord injury
por: Zhang, Yu, et al.
Publicado: (2021)

Deciphering Spinal Endogenous Dopaminergic Mechanisms That Modulate Micturition Reflexes in Rats with Spinal Cord Injury
por: Hou, Shaoping, et al.
Publicado: (2021)

Analysis of potential genetic biomarkers and molecular mechanism of smoking-related postmenopausal osteoporosis using weighted gene co-expression network analysis and machine learning
por: Li, Shaoshuo, et al.
Publicado: (2021)

Network pharmacology integrated with experimental validation to explore the therapeutic role and potential mechanism of Epimedium for spinal cord injury
por: Fu, Xuanhao, et al.
Publicado: (2023)

Deciphering the Pharmacological Mechanisms of Guizhi-Fuling Capsule on Primary Dysmenorrhea Through Network Pharmacology
por: Zhang, Siqin, et al.
Publicado: (2021)

Exploration of the effect and potential mechanism of quercetin in repairing spinal cord injury based on network pharmacology and in vivo experimental verification
por: Shen, Wenyuan, et al.
Publicado: (2023)

Corrigendum: Network pharmacology integrated with experimental validation to explore the therapeutic role and potential mechanism of Epimedium for spinal cord injury
por: Fu, Xuanhao, et al.
Publicado: (2023)

The mechanisms of Chuanxiong Rhizoma in treating spinal cord injury based on network pharmacology and experimental verification
por: Tao, Bo, et al.
Publicado: (2021)

Urolithin A as a Potential Drug for the Treatment of Spinal Cord Injuries: A Mechanistic Study Using Network Pharmacology Approaches
por: Mao, Chao, et al.
Publicado: (2022)

Exploring the mechanism of Buyang Huanwu Decoction in the treatment of spinal cord injury based on network pharmacology and molecular docking
por: Wang, Ying, et al.
Publicado: (2022)

Potential targets and mechanisms of photobiomodulation for spinal cord injury
por: Ju, Cheng, et al.
Publicado: (2022)

Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation
por: Wang, Zihao, et al.
Publicado: (2019)

A network pharmacology perspective for deciphering potential mechanisms of action of Solanum nigrum L. in bladder cancer
por: Dong, Yang, et al.
Publicado: (2021)

Acute spinal cord injury: Pathophysiology and pharmacological intervention
por: Zhang, Yi, et al.
Publicado: (2021)

Network Pharmacology Integrated with Transcriptomics Deciphered the Potential Mechanism of Codonopsis pilosula against Hepatocellular Carcinoma
por: Liu, Zhili, et al.
Publicado: (2022)

Network Pharmacology Deciphering Mechanisms of Volatiles of Wendan Granule for the Treatment of Alzheimer's Disease
por: Liu, Jun-feng, et al.
Publicado: (2019)

Pharmacological and non-pharmacological therapeutic interventions for the treatment of spinal cord injury-induced pain
por: Eller, Olivia C., et al.
Publicado: (2022)

Deciphering the pharmacological mechanisms of Fraxini Cortex for ulcerative colitis treatment based on network pharmacology and in vivo studies
por: Wang, Tianming, et al.
Publicado: (2023)

Deciphering the underlying mechanism of Xianlinggubao capsule against osteoporosis by network pharmacology
por: Bao, Hangsheng, et al.
Publicado: (2020)

Systematic review and comparison of pharmacologic therapies for neuropathic pain associated with spinal cord injury
por: Snedecor, Sonya J, et al.
Publicado: (2013)

Deciphering the Underlying Mechanisms of Formula Le-Cao-Shi Against Liver Injuries by Integrating Network Pharmacology, Metabonomics, and Experimental Validation
por: Zhao, Qing, et al.
Publicado: (2022)

An Overview of Pharmacological Approaches for Management and Repair of Spinal Cord Injuries
por: Khoshnevisan, Alireza, et al.
Publicado: (2010)

Pharmacologic and Acute Management of Spinal Cord Injury in Adults and Children
por: Thomas, Ajay X., et al.
Publicado: (2022)

The Dorsal Column Lesion Model of Spinal Cord Injury and Its Use in Deciphering the Neuron‐Intrinsic Injury Response
por: Attwell, Callan L., et al.
Publicado: (2018)

The Potential of Curcumin in Treatment of Spinal Cord Injury
por: Sanivarapu, Raghavendra, et al.
Publicado: (2016)

Deciphering the Underlying Mechanism of Eucommiae Cortex against Osteoporotic Fracture by Network Pharmacology
por: Shuai, Yongming, et al.
Publicado: (2020)

Deciphering the pharmacological mechanisms of Chaenomeles Fructus against rheumatoid arthritis by integrating network pharmacology and experimental validation
por: Sun, Mengjia, et al.
Publicado: (2022)

An emerging role of inflammasomes in spinal cord injury and spinal cord tumor
por: Chen, Jiansong, et al.
Publicado: (2023)

Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury
por: Wang, Rongrong, et al.
Publicado: (2023)

Mechanism of Ferroptosis and Its Role in Spinal Cord Injury
por: Li, Fei, et al.
Publicado: (2022)

Comparative efficacy and safety of topical hemostatic agents in primary total knee arthroplasty: A network meta-analysis of randomized controlled trials
por: Li, Shaoshuo, et al.
Publicado: (2021)

Mechanisms of spinal cord injury regeneration in zebrafish: a systematic review
por: Noorimotlagh, Zeynab, et al.
Publicado: (2017)

Deciphering the Efficacy and Mechanism of Astragalus membranaceus on High Altitude Polycythemia by Integrating Network Pharmacology and In Vivo Experiments
por: Liu, Xiru, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking-Based Investigation of Potential Targets of Astragalus membranaceus and Angelica sinensis Compound Acting on Spinal Cord Injury
por: Cao, Shengnan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nc4mn7r5g5nujfp1e1vq15vo3p