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Inhibition of the NADPH Oxidase Pathway Reduces Ferroptosis during Septic Renal Injury in Diabetic Mice
BACKGROUND: Obesity and type 2 diabetes mellitus (DM) contribute to a higher mortality rate in patients with septic acute kidney injury (AKI) during sepsis. Reactive oxygen species (ROS) is the major injury factor for sepsis. This study was aimed at exploring the potential therapeutic drug for septi...
Autores principales: | Yao, Weifeng, Liao, Haofeng, Pang, Mengya, Pan, Lijie, Guan, Yu, Huang, Xiaolei, Hei, Ziqing, Luo, Chenfang, Ge, Mian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898803/ https://www.ncbi.nlm.nih.gov/pubmed/35265258 http://dx.doi.org/10.1155/2022/1193734 |
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