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Inhibition of the NADPH Oxidase Pathway Reduces Ferroptosis during Septic Renal Injury in Diabetic Mice

BACKGROUND: Obesity and type 2 diabetes mellitus (DM) contribute to a higher mortality rate in patients with septic acute kidney injury (AKI) during sepsis. Reactive oxygen species (ROS) is the major injury factor for sepsis. This study was aimed at exploring the potential therapeutic drug for septi...

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Detalles Bibliográficos
Autores principales: Yao, Weifeng, Liao, Haofeng, Pang, Mengya, Pan, Lijie, Guan, Yu, Huang, Xiaolei, Hei, Ziqing, Luo, Chenfang, Ge, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898803/
https://www.ncbi.nlm.nih.gov/pubmed/35265258
http://dx.doi.org/10.1155/2022/1193734

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