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A Semi-supervised Deep Learning Method for Cervical Cell Classification

Currently, the Thinprep cytologic test (TCT) is the most popular cervical cancer cytology test technique. It can detect precancerous conditions and microbial infections. However, this technique entirely relies on manual operation and doctors' naked eye observation, resulting in a heavy workload...

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Detalles Bibliográficos
Autores principales: Zhao, Siqi, He, Yongjun, Qin, Jian, Wang, Zixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898884/
https://www.ncbi.nlm.nih.gov/pubmed/35265455
http://dx.doi.org/10.1155/2022/4376178
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author Zhao, Siqi
He, Yongjun
Qin, Jian
Wang, Zixuan
author_facet Zhao, Siqi
He, Yongjun
Qin, Jian
Wang, Zixuan
author_sort Zhao, Siqi
collection PubMed
description Currently, the Thinprep cytologic test (TCT) is the most popular cervical cancer cytology test technique. It can detect precancerous conditions and microbial infections. However, this technique entirely relies on manual operation and doctors' naked eye observation, resulting in a heavy workload and low accuracy rate. Recently, automatic pathological diagnosis has been developed to solve this problem. Cervical cell classification is a key technology in the intelligent cervical cancer diagnosis system. Training a deep neural network-based classification model requires a large amount of data. However, cervical cell labeling requires specialized physicians and the cost of labeling is high, resulting in a lack of sufficient labeling data in this field. To address this problem, we propose a method to ensure high accuracy in cervical cell classification with a small amount of labeled data by introducing manual features and a voting mechanism to achieve data expansion in semi-supervised learning. The method consists of three main steps, using a clarity function to filter out high-quality cervical cell images, annotating a small amount of them, and balancing the training data using a voting mechanism. With a small amount of labeled data, the accuracy of the proposed method in this paper can reach to 91.94%.
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spelling pubmed-88988842022-03-08 A Semi-supervised Deep Learning Method for Cervical Cell Classification Zhao, Siqi He, Yongjun Qin, Jian Wang, Zixuan Anal Cell Pathol (Amst) Research Article Currently, the Thinprep cytologic test (TCT) is the most popular cervical cancer cytology test technique. It can detect precancerous conditions and microbial infections. However, this technique entirely relies on manual operation and doctors' naked eye observation, resulting in a heavy workload and low accuracy rate. Recently, automatic pathological diagnosis has been developed to solve this problem. Cervical cell classification is a key technology in the intelligent cervical cancer diagnosis system. Training a deep neural network-based classification model requires a large amount of data. However, cervical cell labeling requires specialized physicians and the cost of labeling is high, resulting in a lack of sufficient labeling data in this field. To address this problem, we propose a method to ensure high accuracy in cervical cell classification with a small amount of labeled data by introducing manual features and a voting mechanism to achieve data expansion in semi-supervised learning. The method consists of three main steps, using a clarity function to filter out high-quality cervical cell images, annotating a small amount of them, and balancing the training data using a voting mechanism. With a small amount of labeled data, the accuracy of the proposed method in this paper can reach to 91.94%. Hindawi 2022-02-27 /pmc/articles/PMC8898884/ /pubmed/35265455 http://dx.doi.org/10.1155/2022/4376178 Text en Copyright © 2022 Siqi Zhao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhao, Siqi
He, Yongjun
Qin, Jian
Wang, Zixuan
A Semi-supervised Deep Learning Method for Cervical Cell Classification
title A Semi-supervised Deep Learning Method for Cervical Cell Classification
title_full A Semi-supervised Deep Learning Method for Cervical Cell Classification
title_fullStr A Semi-supervised Deep Learning Method for Cervical Cell Classification
title_full_unstemmed A Semi-supervised Deep Learning Method for Cervical Cell Classification
title_short A Semi-supervised Deep Learning Method for Cervical Cell Classification
title_sort semi-supervised deep learning method for cervical cell classification
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898884/
https://www.ncbi.nlm.nih.gov/pubmed/35265455
http://dx.doi.org/10.1155/2022/4376178
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