Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects

Valproic acid (VPA, valproate, Depakote) is a commonly used anti-seizure medication (ASM) in the treatment of epilepsy and a variety of other neurological disorders. While VPA and other ASMs are efficacious for management of seizures, they also increase the risk for adverse pregnancy outcomes, inclu...

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Detalles Bibliográficos
Autores principales: Steele, John W., Lin, Ying Linda, Chen, Nellie, Wlodarczyk, Bogdan J., Chen, Qiuying, Attarwala, Nabeel, Venkatesalu, Madhu, Cabrera, Robert M., Gross, Steven S., Finnell, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898900/
https://www.ncbi.nlm.nih.gov/pubmed/35265619
http://dx.doi.org/10.3389/fcell.2022.832492

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