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Neo-Splicetopes in Tumor Therapy: A Lost Case?
Proteasome generates spliced peptides by ligating two distant cleavage products in a reverse proteolysis reaction. The observation that CD8+ T cells recognizing a spliced peptide induced T cell rejection in a melanoma patient following adoptive T cell transfer (ATT), raised some hopes with regard to...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898901/ https://www.ncbi.nlm.nih.gov/pubmed/35265089 http://dx.doi.org/10.3389/fimmu.2022.849863 |