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Bone mineral: A trojan horse for bone cancers. Efficient mitochondria targeted delivery and tumor eradication with nano hydroxyapatite containing doxorubicin

Efficient systemic pharmacological treatment of solid tumors is hampered by inadequate tumor concentration of cytostatics necessitating development of smart local drug delivery systems. To overcome this, we demonstrate that doxorubicin (DOX), a cornerstone drug used for osteosarcoma treatment, shows...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Nadeem, Aftab, Sebastian, Sujeesh, Olsson, Martin A., Wai, Sun N., Styring, Emelie, Engellau, Jacob, Isaksson, Hanna, Tägil, Magnus, Lidgren, Lars, Raina, Deepak Bushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898975/
https://www.ncbi.nlm.nih.gov/pubmed/35265825
http://dx.doi.org/10.1016/j.mtbio.2022.100227

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