Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand

TNF-related apoptosis inducing ligand (TRAIL) is expressed on cytotoxic T lymphocytes (CTLs) and TRAIL is linked to progression of diabetes. However, the impact of high glucose on TRAIL expression and its related killing function in CTLs still remains largely elusive. Here, we report that TRAIL is s...

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Detalles Bibliográficos
Autores principales: Yang, Wenjuan, Denger, Andreas, Diener, Caroline, Küppers, Frederic, Soriano-Baguet, Leticia, Schäfer, Gertrud, Yanamandra, Archana K., Zhao, Renping, Knörck, Arne, Schwarz, Eva C., Hart, Martin, Lammert, Frank, Roma, Leticia Prates, Brenner, Dirk, Christidis, Grigorios, Helms, Volkhard, Meese, Eckart, Hoth, Markus, Qu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899024/
https://www.ncbi.nlm.nih.gov/pubmed/35265081
http://dx.doi.org/10.3389/fimmu.2022.831680

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