Programmed Exercise Attenuates Familial Hypertrophic Cardiomyopathy in Transgenic E22K Mice via Inhibition of PKC-α/NFAT Pathway

Familial hypertrophic cardiomyopathy (FHCM), an autosomal dominant disease, is caused by mutations in genes encoding cardiac sarcomeric proteins. E22K, a mutation in the myosin regulatory light chain sarcomere gene, is associated with the development of FHCM. However, the molecular mechanisms by whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Haiying, Lin, Yuedong, Zhang, Ran, Chen, Yafen, Ji, Wei, Li, Shenwei, Wang, Li, Tan, Rubin, Yuan, Jinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899095/
https://www.ncbi.nlm.nih.gov/pubmed/35265680
http://dx.doi.org/10.3389/fcvm.2022.808163

Ejemplares similares

Ejemplares similares