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Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson’s disease
Parkinson's disease (PD) is caused by the loss of dopaminergic (DA) neurons in the substantia nigra (SN). Although PD pathogenesis is not fully understood, studies implicate perturbations in gene regulation, mitochondrial function, and neuronal activity. MicroRNAs (miRs) are small gene regulato...
Autores principales: | Stein, Colleen S., McLendon, Jared M., Witmer, Nathan H., Boudreau, Ryan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899134/ https://www.ncbi.nlm.nih.gov/pubmed/35280925 http://dx.doi.org/10.1016/j.omtn.2022.02.007 |
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