Cargando…

Transferrin receptor-mediated internalization and intracellular fate of conjugates of a DNA aptamer

Aptamers have excellent specificity and affinity in targeting cell surface receptors, showing great potential in targeted delivery of drugs, siRNA, mRNA, and various nanomaterials with therapeutic function. A better insight of the receptor-mediated internalization process of aptameric conjugates cou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Nan, Wang, Junyan, Bing, Tao, Liu, Xiangjun, Shangguan, Dihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899136/ https://www.ncbi.nlm.nih.gov/pubmed/35282414 http://dx.doi.org/10.1016/j.omtn.2022.02.006

Ejemplares similares

A DNA Aptameric Ligand of Human Transferrin Receptor Generated by Cell-SELEX
por: Zhang, Nan, et al.
Publicado: (2021)

Structural Optimization and Interaction Study of a DNA Aptamer to L1 Cell Adhesion Molecule
por: Long, Zhenhao, et al.
Publicado: (2023)

DNA Aptamer Evolved by Cell-SELEX for Recognition of Prostate Cancer
por: Wang, Yuanyuan, et al.
Publicado: (2014)

Triplex-quadruplex structural scaffold: a new binding structure of aptamer
por: Bing, Tao, et al.
Publicado: (2017)

An Aptamer That Rapidly Internalizes into Cancer Cells Utilizes the Transferrin Receptor Pathway
por: Song, Xirui, et al.
Publicado: (2023)

Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers
por: Bing, Tao, et al.
Publicado: (2019)

Development of squaraine based G-quadruplex ligands using click chemistry
por: Zhang, Xin, et al.
Publicado: (2017)

Two Interconvertible Folds Modulate the Activity of a DNA Aptamer Against Transferrin Receptor
por: Porciani, David, et al.
Publicado: (2014)

Oxidative degradation of polyamines by serum supplement causes cytotoxicity on cultured cells
por: Wang, Linlin, et al.
Publicado: (2018)

Immunomodulatory Effects of Lycium barbarum Polysaccharide Extract and Its Uptake Behaviors at the Cellular Level
por: Feng, Le, et al.
Publicado: (2020)

Intracellular Metabolism and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugates of Differing Molar Ratios
por: Sasaki, Katsunori, et al.
Publicado: (1993)

Intracellular interactions of transferrin and its receptor during biosynthesis
Publicado: (1990)

Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides
por: Zhang, Nan, et al.
Publicado: (2015)

Comparative Study of the Chemical Constituents and Bioactivities of the Extracts from Fruits, Leaves and Root Barks of Lycium barbarum
por: Xiao, Xiao, et al.
Publicado: (2019)

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes
Publicado: (1983)

Intracellular Fate of Spherical Nucleic Acid Nanoparticle Conjugates
por: Wu, Xiaochen A., et al.
Publicado: (2014)

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells
Publicado: (1983)

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation
por: Park, Eunhee, et al.
Publicado: (2019)

Pulmonary fate and consequences of transferrin-functionalized gold nanoparticles
por: Konduru, Nagarjun Venkata, et al.
Publicado: (2021)

Transferrin Receptor 1 Regulates Thermogenic Capacity and Cell Fate in Brown/Beige Adipocytes
por: Li, Jin, et al.
Publicado: (2020)

Transferrin-Conjugated Polymeric Nanoparticle for Receptor-Mediated Delivery of Doxorubicin in Doxorubicin-Resistant Breast Cancer Cells
por: Soe, Zar Chi, et al.
Publicado: (2019)

Molecular recognition of acute myeloid leukemia using aptamers
por: Sefah, Kwame, et al.
Publicado: (2009)

Trafficking of Siderophore Transporters in Saccharomyces cerevisiae and Intracellular Fate of Ferrioxamine B Conjugates
por: Froissard, Marine, et al.
Publicado: (2007)

Role of Fe, Transferrin and Transferrin Receptor in Anti-Tumor Effect of Vitamin C
por: Qiu, Jia, et al.
Publicado: (2022)

Rapid endocytosis of the transferrin receptor in the absence of bound transferrin
Publicado: (1985)

Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor
Publicado: (1987)

The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain
Publicado: (1994)

Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX
por: Lyu, Yifan, et al.
Publicado: (2016)

Kinetics of Internalization and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugate in Human Leukemia Cell Line, K562
por: Kohgo, Yutaka, et al.
Publicado: (1990)

Dicyanomethylene Substituted Benzothiazole Squaraines: The Efficiency of Photodynamic Therapy In Vitro and In Vivo
por: Wei, Yongbiao, et al.
Publicado: (2017)

Transferrin Receptors in Erythropoiesis
por: Richard, Cyrielle, et al.
Publicado: (2020)

Role of transferrin, transferrin receptors, and iron in macrophage listericidal activity
Publicado: (1991)

Visualization of internalization of functionalized cobalt ferrite nanoparticles and their intracellular fate
por: Bregar, Vladimir B, et al.
Publicado: (2013)

Selection of a Novel DNA Aptamer for Assay of Intracellular Interferon-Gamma
por: Cao, Beibei, et al.
Publicado: (2014)

Using modified aptamers for site specific protein–aptamer conjugations
por: Wang, Ruowen, et al.
Publicado: (2016)

Aptamer–Gemcitabine Conjugates with Enzymatically Cleavable Linker for Targeted Delivery and Intracellular Drug Release in Cancer Cells
por: Qi, Jianjun, et al.
Publicado: (2022)

Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells
Publicado: (1985)

Affibody Molecules Intended for Receptor-Mediated Transcytosis via the Transferrin Receptor
por: Hjelm, Linnea Charlotta, et al.
Publicado: (2023)

Transferrin-binding protein complex is the receptor for transferrin uptake in Trypanosoma brucei
Publicado: (1995)

Intracellular DNA Damage by Lysine-Acetylene Conjugates
por: Yang, Wang-Yong, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_nr8duddkmlncds2kt3csdvrn5l