Ageing causes an aortic contractile dysfunction phenotype by targeting the expression of members of the extracellular signal‐regulated kinase pathway

The extracellular signal‐regulated kinase (ERK) pathway is a well‐known regulator of vascular smooth muscle cell proliferation, but it also serves as a regulator of caldesmon, which negatively regulates vascular contractility. This study examined whether aortic contractile function requires ERK acti...

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Detalles Bibliográficos
Autores principales: Nicholson, Christopher J., Xing, Yi, Lee, Sophie, Liang, Stephanie, Mohan, Shivani, O’Rourke, Caitlin, Kang, Joshua, Morgan, Kathleen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899171/
https://www.ncbi.nlm.nih.gov/pubmed/35181997
http://dx.doi.org/10.1111/jcmm.17118

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