Acetylshikonin induces autophagy‐dependent apoptosis through the key LKB1‐AMPK and PI3K/Akt‐regulated mTOR signalling pathways in HL‐60 cells

Acetylshikonin (ASK) is a natural naphthoquinone derivative of traditional Chinese medicine Lithospermum erythrorhyzon. It has been reported that ASK has bactericidal, anti‐inflammatory and antitumour effects. However, whether ASK induces apoptosis and autophagy in acute myeloid leukaemia (AML) cell...

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Detalles Bibliográficos
Autores principales: Wu, Meng‐Di, Zhang, Yuan‐Ying, Yi, Shu‐Ying, Sun, Bei‐Bei, Lan, Jing, Jiang, Han‐Ming, Hao, Gang‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899184/
https://www.ncbi.nlm.nih.gov/pubmed/35106915
http://dx.doi.org/10.1111/jcmm.17202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899184/
https://www.ncbi.nlm.nih.gov/pubmed/35106915
http://dx.doi.org/10.1111/jcmm.17202

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