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3BDO inhibits the proliferation, epithelial-mesenchymal transition (EMT), and stemness via suppressing survivin in human glioblastoma cells

Background: Glioblastoma (GBM) is a tumor of the central nervous system with an extremely poor prognosis. Stemness and EMT play important roles in GBM progression. 3-benzyl-5-((2-nitrophenoxy) methyl) dihydrofuran-2(3H)-one (3BDO), an autophagy inhibitor, has been reported to exert anti-cancer activ...

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Detalles Bibliográficos
Autores principales: Wang, Zhaotao, Li, Yongping, Liu, Minyi, Chen, Danmin, Lu, Jiajie, Ji, Yunxiang, Xing, Zhou, Wang, Yezhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899367/
https://www.ncbi.nlm.nih.gov/pubmed/35281871
http://dx.doi.org/10.7150/jca.66674