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Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase 1A1

Human UDP-glucuronosyltransferase 1A1 (hUGT1A1) is one of the most essential phase II enzymes in humans. Dysfunction or strong inhibition of hUGT1A1 may result in hyperbilirubinaemia and clinically relevant drug/herb-drug interactions (DDIs/HDIs). Recently, a high-throughput fluorescence-based assay...

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Detalles Bibliográficos
Autores principales:	Pang, Hui-Lin, Zhu, Guang-Hao, Zhou, Qi-Hang, Ai, Chun-Zhi, Zhu, Ya-Di, Wang, Ping, Dou, Tong-Yi, Xia, Yang-Liu, Ma, Hong, Ge, Guang-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899474/ https://www.ncbi.nlm.nih.gov/pubmed/35264954 http://dx.doi.org/10.3389/fphar.2022.815235

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