ATXN2-mediated translation of TNFR1 promotes esophageal squamous cell carcinoma via m(6)A-dependent manner

N(6)-methyladenosine (m(6)A) is the most prevalent RNA modification, and the effect of its dysregulation on esophageal squamous cell carcinoma (ESCC) development remains unclear. Here, by performing transcriptome-wide m(6)A sequencing in 16 ESCC tissue samples, we identified the key roles of m(6)A i...

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Detalles Bibliográficos
Autores principales: Li, Rui, Zeng, Lingxing, Zhao, Hongzhe, Deng, Junge, Pan, Ling, Zhang, Shaoping, Wu, Guandi, Ye, Ying, Zhang, Jialiang, Su, Jiachun, Zheng, Yanfen, Deng, Shuang, Bai, Ruihong, Zhuang, Lisha, Li, Mei, Zuo, Zhixiang, Lin, Dongxin, Zheng, Jian, Huang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899599/
https://www.ncbi.nlm.nih.gov/pubmed/34995801
http://dx.doi.org/10.1016/j.ymthe.2022.01.006

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