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Safety and efficacy of tenecteplase versus alteplase in patients with acute ischaemic stroke (TRACE): a multicentre, randomised, open label, blinded-endpoint (PROBE) controlled phase II study

BACKGROUND: Tenecteplase (TNK) possesses several pharmacological characteristics superior to conventional alteplase (rt-PA), with well-established safety and efficacy profile in Caucasians. There exists controversy over the optimal dose of intravenous rt-PA for East Asians with acute ischaemic strok...

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Detalles Bibliográficos
Autores principales: Li, Shuya, Pan, Yuesong, Wang, Ziran, Liang, Zhigang, Chen, Huisheng, Wang, Dong, Sui, Yi, Zhao, Xingquan, Wang, Yilong, Du, WanLiang, Zheng, Huaguang, Wang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899644/
https://www.ncbi.nlm.nih.gov/pubmed/34429364
http://dx.doi.org/10.1136/svn-2021-000978