Cargando…

Dual Orexin Receptor Antagonist Attenuates Increases in IOP, ICP, and Translaminar Pressure Difference After Stimulation of the Hypothalamus in Rats

PURPOSE: Intraocular pressure (IOP) remains the only modifiable risk factor for glaucoma progression. Our previous discovery that stimulation of nuclei within the hypothalamus can modulate IOP, intracranial pressure (ICP), and translaminar pressure difference (TLPD) fluctuations led us to investigat...

Descripción completa

Detalles Bibliográficos
Autores principales:	DeCarlo, Arthur A., Hammes, Nathan, Johnson, Philip L., Shekhar, Anantha, Samuels, Brian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899853/ https://www.ncbi.nlm.nih.gov/pubmed/35234838 http://dx.doi.org/10.1167/iovs.63.3.1

Ejemplares similares

Effect of Body Position on Intraocular Pressure (IOP), Intracranial Pressure (ICP), and Translaminar Pressure (TLP) Via Continuous Wireless Telemetry in Nonhuman Primates (NHPs)
por: Jasien, Jessica V., et al.
Publicado: (2020)

Diurnal Cycle of Translaminar Pressure in Nonhuman Primates Quantified With Continuous Wireless Telemetry
por: Jasien, Jessica V., et al.
Publicado: (2020)

The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry
por: Turner, Daniel C., et al.
Publicado: (2017)

Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System
por: Ikegami, Keisuke, et al.
Publicado: (2020)

Implanted Microsensor Continuous IOP Telemetry Suggests Gaze and Eyelid Closure Effects on IOP—A Preliminary Study
por: van den Bosch, Jacqueline J. O. N., et al.
Publicado: (2021)

Identifying the Critical Factors Governing Translaminar Pressure Differential Through a Compartmental Model
por: Kaskar, Omkar G., et al.
Publicado: (2019)

Optic Nerve Head Gene Transcription Sequelae to a Single Elevated IOP Exposure Provides Insights Into Known Responses to Chronically Elevated IOP
por: Lozano, Diana C., et al.
Publicado: (2023)

Ocular Pulse Amplitude Correlates With Ocular Rigidity at Native IOP Despite the Variability in Intraocular Pulse Volume With Each Heartbeat
por: Markert, John E., et al.
Publicado: (2022)

Trabeculotomy opening size and IOP reduction after Trabectome® surgery
por: Wecker, Thomas, et al.
Publicado: (2017)

Inter-eye correlation analysis of 24-h IOPs and glaucoma progression
por: Dakroub, Mohamad, et al.
Publicado: (2022)

Comparing Acute IOP-Induced Lamina Cribrosa Deformations Premortem and Postmortem
por: Wei, Junchao, et al.
Publicado: (2022)

Regional Deformation of the Optic Nerve Head and Peripapillary Sclera During IOP Elevation
por: Pavlatos, Elias, et al.
Publicado: (2018)

ABCA1 Regulates IOP by Modulating Cav1/eNOS/NO Signaling Pathway
por: Hu, Chunchun, et al.
Publicado: (2020)

Mechanical Deformation of Human Optic Nerve Head and Peripapillary Tissue in Response to Acute IOP Elevation
por: Ma, Yanhui, et al.
Publicado: (2019)

Osthole Reduces Mouse IOP Associated With Ameliorating Extracellular Matrix Expression of Trabecular Meshwork Cell
por: Fan, Yuchen, et al.
Publicado: (2020)

So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult
por: Voorhees, Andrew P., et al.
Publicado: (2020)

Intracameral Injection of AAV-DJ.COMP-ANG1 Reduces the IOP of Mice by Reshaping the Trabecular Outflow Pathway
por: Qiao, Yunsheng, et al.
Publicado: (2022)

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice
por: De Groef, Lies, et al.
Publicado: (2016)

A Period of Controlled Elevation of IOP (CEI) Produces the Specific Gene Expression Responses and Focal Injury Pattern of Experimental Rat Glaucoma
por: Morrison, John C., et al.
Publicado: (2016)

Three-Dimensional Ultrasound Elastography Detects Age-Related Increase in Anterior Peripapillary Sclera and Optic Nerve Head Compression During IOP Elevation
por: Kwok, Sunny, et al.
Publicado: (2023)

Significance of non-intraocular pressure (IOP)-related factors particularly in normal tension glaucoma: Looking beyond IOP
por: Dinakaran, Shoruba, et al.
Publicado: (2022)

Systemic Alpha1-Adrenoceptor Antagonists and Increased Risk of Open-Angle Glaucoma: A Nationwide Population-Based Cohort Study
por: Lin, Hong-Zin, et al.
Publicado: (2020)

Single- and Dual-Task Gait Performance in Patients With Open-Angle Glaucoma: A Cross-sectional Study
por: Freitag, Constantin W., et al.
Publicado: (2023)

A Novel Tree Shrew (Tupaia belangeri) Model of Glaucoma
por: Samuels, Brian C., et al.
Publicado: (2018)

Longitudinal Changes of Bruch's Membrane Opening, Anterior Scleral Canal Opening, and Border Tissue in Experimental Juvenile High Myopia
por: KhalafAllah, Mahmoud T., et al.
Publicado: (2023)

DPP-4 Inhibitors Attenuate Fibrosis After Glaucoma Filtering Surgery by Suppressing the TGF-β/Smad Signaling Pathway
por: Yoshida, Masaaki, et al.
Publicado: (2023)

The Roles Played by FP/EP3 Receptors During Pressure-lowering in Mouse Eyes Mediated by a Dual FP/EP3 Receptor Agonist
por: Yamagishi-Kimura, Reiko, et al.
Publicado: (2022)

Trabeculectomy versus Xen gel implant for the treatment of open-angle glaucoma: a 3-year retrospective analysis
por: Cappelli, Francesca, et al.
Publicado: (2022)

Role of the Orexin System on the Hypothalamus-Pituitary-Thyroid Axis
por: Messina, Antonietta, et al.
Publicado: (2016)

The Dual Orexin/Hypocretin Receptor Antagonist, Almorexant, in the Ventral Tegmental Area Attenuates Ethanol Self-Administration
por: Srinivasan, Subhashini, et al.
Publicado: (2012)

Comparison of Aqueous Outflow Facility Measurement by Pneumatonography and Digital Schiøtz Tonography
por: Kazemi, Arash, et al.
Publicado: (2017)

Associations of Midlife and Late-Life Blood Pressure Status With Late-Life Retinal OCT Measures
por: Pan-Doh, Nathan, et al.
Publicado: (2023)

Outcomes of a combination of augmented MicroPulse and limited Continuous Wave Cyclophotocoagulation in patients with refractory glaucoma
por: Gupta, Sanchay, et al.
Publicado: (2021)

Is Genetic Risk for Sleep Apnea Causally Linked With Glaucoma Susceptibility?
por: Ingold, Nathan, et al.
Publicado: (2022)

Orexin, orexin receptor antagonists and central cardiovascular control
por: Carrive, Pascal
Publicado: (2013)

An In Vitro Perfusion System to Enhance Outflow Studies in Mouse Eyes
por: Kizhatil, Krishnakumar, et al.
Publicado: (2016)

Semantic segmentation of gonio-photographs via adaptive ROI localisation and uncertainty estimation
por: Peroni, Andrea, et al.
Publicado: (2021)

Neurodegeneration Markers Galectin-3 and Apolipoprotein E Are Elevated in the Aqueous Humor of Eyes With Glaucoma
por: Pitts, Kristen M., et al.
Publicado: (2022)

Kinetic properties of “dual” orexin receptor antagonists at OX(1)R and OX(2)R orexin receptors
por: Callander, Gabrielle E., et al.
Publicado: (2013)

Hypothalamus-Olfactory System Crosstalk: Orexin A Immunostaining in Mice
por: Gascuel, Jean, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_31di33p2ca3n2lhevgtqj73691