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Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study

OBJECTIVES: This study aimed to determine the variation in the interval between the onset of symptoms and clinical presentation, and its associated factors among symptomatic individuals with gonorrhoea. DESIGN: A cross-sectional study was conducted between 1 June and 30 July 2017. SETTING: 129 sexua...

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Autores principales: Zhao, Peizhen, Nie, Juan, Cheng, Huanhuan, Tang, Weiming, Zheng, Heping, Yang, Bin, Wang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900027/
https://www.ncbi.nlm.nih.gov/pubmed/35246417
http://dx.doi.org/10.1136/bmjopen-2021-052586
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author Zhao, Peizhen
Nie, Juan
Cheng, Huanhuan
Tang, Weiming
Zheng, Heping
Yang, Bin
Wang, Cheng
author_facet Zhao, Peizhen
Nie, Juan
Cheng, Huanhuan
Tang, Weiming
Zheng, Heping
Yang, Bin
Wang, Cheng
author_sort Zhao, Peizhen
collection PubMed
description OBJECTIVES: This study aimed to determine the variation in the interval between the onset of symptoms and clinical presentation, and its associated factors among symptomatic individuals with gonorrhoea. DESIGN: A cross-sectional study was conducted between 1 June and 30 July 2017. SETTING: 129 sexually transmitted disease clinics from 21 cities of Guangdong, China. PARTICIPANTS: Using convenience sampling method to recruit symptomatic individuals with gonorrhoea over 18 years old. OUTCOME MEASURE: Time to clinical presentation. RESULTS: Among 1664 participants, the median age was 29 (24–36) years old, and the majority were male (92.5%) and married (52.9%). The median time to clinical presentation was 3 (2–6) days. About 471 (28.3%) patients had sexual contact while symptomatic. After adjusting for covariates, participants who were female (aβ=0.44, 95% CI: 0.22 to 0.80), from east Guangdong region (aβ=0.44, 95% CI: 0.22 to 0.80) and had the absence of dysuria (aβ=0.26, 95% CI: 0.06 to 0.46) had increased time to clinical presentation. Participants who had commercial sex in the past 6 months (aβ=−0.11, 95% CI: −0.21 to –0.01) had decreased time to clinical presentation. Participants who were female (adjusted odds ratio (aOR)=1.66, 95% CI: 1.08 to 2.50) and delayed in seeking healthcare more than 7 days (aOR=46.71, 95% CI: 24.27 to 89.93) were more likely to have sexual contact while symptomatic. CONCLUSION: The time to clinical presentation for individuals with symptomatic gonorrhoea is variable and a high proportion of participants continued to have sexual behaviour while symptomatic. Strategies to increase health literacy may help to minimise the sequelae of gonorrhoea and reduce onward transmission.
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spelling pubmed-89000272022-03-22 Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study Zhao, Peizhen Nie, Juan Cheng, Huanhuan Tang, Weiming Zheng, Heping Yang, Bin Wang, Cheng BMJ Open Epidemiology OBJECTIVES: This study aimed to determine the variation in the interval between the onset of symptoms and clinical presentation, and its associated factors among symptomatic individuals with gonorrhoea. DESIGN: A cross-sectional study was conducted between 1 June and 30 July 2017. SETTING: 129 sexually transmitted disease clinics from 21 cities of Guangdong, China. PARTICIPANTS: Using convenience sampling method to recruit symptomatic individuals with gonorrhoea over 18 years old. OUTCOME MEASURE: Time to clinical presentation. RESULTS: Among 1664 participants, the median age was 29 (24–36) years old, and the majority were male (92.5%) and married (52.9%). The median time to clinical presentation was 3 (2–6) days. About 471 (28.3%) patients had sexual contact while symptomatic. After adjusting for covariates, participants who were female (aβ=0.44, 95% CI: 0.22 to 0.80), from east Guangdong region (aβ=0.44, 95% CI: 0.22 to 0.80) and had the absence of dysuria (aβ=0.26, 95% CI: 0.06 to 0.46) had increased time to clinical presentation. Participants who had commercial sex in the past 6 months (aβ=−0.11, 95% CI: −0.21 to –0.01) had decreased time to clinical presentation. Participants who were female (adjusted odds ratio (aOR)=1.66, 95% CI: 1.08 to 2.50) and delayed in seeking healthcare more than 7 days (aOR=46.71, 95% CI: 24.27 to 89.93) were more likely to have sexual contact while symptomatic. CONCLUSION: The time to clinical presentation for individuals with symptomatic gonorrhoea is variable and a high proportion of participants continued to have sexual behaviour while symptomatic. Strategies to increase health literacy may help to minimise the sequelae of gonorrhoea and reduce onward transmission. BMJ Publishing Group 2022-03-04 /pmc/articles/PMC8900027/ /pubmed/35246417 http://dx.doi.org/10.1136/bmjopen-2021-052586 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Epidemiology
Zhao, Peizhen
Nie, Juan
Cheng, Huanhuan
Tang, Weiming
Zheng, Heping
Yang, Bin
Wang, Cheng
Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study
title Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study
title_full Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study
title_fullStr Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study
title_full_unstemmed Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study
title_short Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study
title_sort correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in south china: results from a cross-sectional study
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900027/
https://www.ncbi.nlm.nih.gov/pubmed/35246417
http://dx.doi.org/10.1136/bmjopen-2021-052586
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