Aberrations in SMAD family of genes among HNSCC patients

Head and neck cancer is a debilitating disease with several etiological factors. One of the main etiologies to be noticed is the alteration, which is either caused by genetic or environmental factors. Therefore, it is of interest to assess the effect of genetic alterations, especially the non-synony...

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Autores principales: Thariny, E, Smiline Girija, AM, Paramasivam, A, Vijayashree Priyadharsini, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900164/
https://www.ncbi.nlm.nih.gov/pubmed/35291342
http://dx.doi.org/10.6026/973206300171113
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author Thariny, E
Smiline Girija, AM
Paramasivam, A
Vijayashree Priyadharsini, J
author_facet Thariny, E
Smiline Girija, AM
Paramasivam, A
Vijayashree Priyadharsini, J
author_sort Thariny, E
collection PubMed
description Head and neck cancer is a debilitating disease with several etiological factors. One of the main etiologies to be noticed is the alteration, which is either caused by genetic or environmental factors. Therefore, it is of interest to assess the effect of genetic alterations, especially the non-synonymous mutations of the SMAD gene family and its possible association with HNSCC. Data shows a significant novel mutation in the SMAD gene family in association with head and neck squamous cell carcinoma (HNSCC), which would aid in better diagnosis and treatment planning for cancer.
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spelling pubmed-89001642022-03-14 Aberrations in SMAD family of genes among HNSCC patients Thariny, E Smiline Girija, AM Paramasivam, A Vijayashree Priyadharsini, J Bioinformation Research Article Head and neck cancer is a debilitating disease with several etiological factors. One of the main etiologies to be noticed is the alteration, which is either caused by genetic or environmental factors. Therefore, it is of interest to assess the effect of genetic alterations, especially the non-synonymous mutations of the SMAD gene family and its possible association with HNSCC. Data shows a significant novel mutation in the SMAD gene family in association with head and neck squamous cell carcinoma (HNSCC), which would aid in better diagnosis and treatment planning for cancer. Biomedical Informatics 2021-12-31 /pmc/articles/PMC8900164/ /pubmed/35291342 http://dx.doi.org/10.6026/973206300171113 Text en © 2021 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Thariny, E
Smiline Girija, AM
Paramasivam, A
Vijayashree Priyadharsini, J
Aberrations in SMAD family of genes among HNSCC patients
title Aberrations in SMAD family of genes among HNSCC patients
title_full Aberrations in SMAD family of genes among HNSCC patients
title_fullStr Aberrations in SMAD family of genes among HNSCC patients
title_full_unstemmed Aberrations in SMAD family of genes among HNSCC patients
title_short Aberrations in SMAD family of genes among HNSCC patients
title_sort aberrations in smad family of genes among hnscc patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900164/
https://www.ncbi.nlm.nih.gov/pubmed/35291342
http://dx.doi.org/10.6026/973206300171113
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