Plasma Exosomes Transfer miR-885-3p Targeting the AKT/NFκB Signaling Pathway to Improve the Sensitivity of Intravenous Glucocorticoid Therapy Against Graves Ophthalmopathy

Graves ophthalmopathy (GO), a manifestation of Graves’ disease, is an organ-specific autoimmune disease. Intravenous glucocorticoid therapy (ivGCs) is the first-line treatment for moderate-to-severe and active GO. However, ivGCs is only effective in 70%–80% of GO patients. Insensitive patients who c...

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Detalles Bibliográficos
Autores principales: Sun, Jingxue, Wei, Jiaxing, Zhang, Yaguang, Li, Jingjing, Li, Jian, Yan, Jiazhuo, Guo, Min, Han, Jun, Qiao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900193/
https://www.ncbi.nlm.nih.gov/pubmed/35265076
http://dx.doi.org/10.3389/fimmu.2022.819680

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