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Endothelial superoxide dismutase 2 is decreased in sickle cell disease and regulates fibronectin processing

Sickle cell disease (SCD) is a genetic red blood cell disorder characterized by increased reactive oxygen species (ROS) and a concordant reduction in antioxidant capacity in the endothelium. Superoxide dismutase 2 (SOD2) is a mitochondrial-localized enzyme that catalyzes the dismutation of superoxid...

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Detalles Bibliográficos
Autores principales: Dosunmu-Ogunbi, Atinuke, Yuan, Shuai, Shiwarski, Daniel J, Tashman, Joshua W, Reynolds, Michael, Feinberg, Adam, Novelli, Enrico M, Shiva, Sruti, Straub, Adam C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900267/
https://www.ncbi.nlm.nih.gov/pubmed/35274104
http://dx.doi.org/10.1093/function/zqac005