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Lenvatinib inhibits the growth of gastric cancer patient-derived xenografts generated from a heterogeneous population
BACKGROUND: Lenvatinib is a multitargeted tyrosine kinase inhibitor that is being tested in combination with immune checkpoint inhibitors to treat advanced gastric cancer; however, little data exists regarding the efficacy of lenvatinib monotherapy. Patient-derived xenografts (PDX) are established b...
Autores principales: | Karalis, John D., Yoon, Lynn Y., Hammer, Suntrea T. G., Hong, Changjin, Zhu, Min, Nassour, Ibrahim, Ju, Michelle R., Xiao, Shu, Castro-Dubon, Esther C., Agrawal, Deepak, Suarez, Jorge, Reznik, Scott I., Mansour, John C., Polanco, Patricio M., Yopp, Adam C., Zeh, Herbert J., Hwang, Tae Hyun, Zhu, Hao, Porembka, Matthew R., Wang, Sam C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900296/ https://www.ncbi.nlm.nih.gov/pubmed/35255940 http://dx.doi.org/10.1186/s12967-022-03317-7 |
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