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Protocol variations in run-on transcription dataset preparation produce detectable signatures in sequencing libraries
BACKGROUND: A variety of protocols exist for producing whole genome run-on transcription datasets. However, little is known about how differences between these protocols affect the signal within the resulting libraries. RESULTS: Using run-on transcription datasets generated from the same biological...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900324/ https://www.ncbi.nlm.nih.gov/pubmed/35255806 http://dx.doi.org/10.1186/s12864-022-08352-8 |