Protocol variations in run-on transcription dataset preparation produce detectable signatures in sequencing libraries

BACKGROUND: A variety of protocols exist for producing whole genome run-on transcription datasets. However, little is known about how differences between these protocols affect the signal within the resulting libraries. RESULTS: Using run-on transcription datasets generated from the same biological...

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Detalles Bibliográficos
Autores principales: Hunter, Samuel, Sigauke, Rutendo F., Stanley, Jacob T., Allen, Mary A., Dowell, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900324/
https://www.ncbi.nlm.nih.gov/pubmed/35255806
http://dx.doi.org/10.1186/s12864-022-08352-8

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