Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model

BACKGROUND: Lymphatic dysfunction exists in tumor necrosis factor transgenic (TNF-Tg) mice and rheumatoid arthritis (RA) patients. While joint-draining TNF-Tg popliteal lymphatic vessels (PLVs) have deficits in contractility during end-stage arthritis, the nature of lymphatic muscle cells (LMCs) and...

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Detalles Bibliográficos
Autores principales: Kenney, H. Mark, Wu, Chia-Lung, Loiselle, Alayna E., Xing, Lianping, Ritchlin, Christopher T., Schwarz, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900348/
https://www.ncbi.nlm.nih.gov/pubmed/35255954
http://dx.doi.org/10.1186/s13075-022-02730-z

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