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Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts

BACKGROUND: Androgenetic alopecia (AGA) is a genetic disorder caused by dihydrotestosterone (DHT), accompanied by the senescence of androgen-sensitive dermal papilla cells (DPCs) located in the base of hair follicles. DHT causes DPC senescence in AGA through mitochondrial dysfunction. However, the m...

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Detalles Bibliográficos
Autores principales: Jung, Young Hyun, Chae, Chang Woo, Choi, Gee Euhn, Shin, Him Cha, Lim, Jae Ryong, Chang, Han Seung, Park, Joonmo, Cho, Ji Hyeon, Park, Mo Ran, Lee, Hyun Jik, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900350/
https://www.ncbi.nlm.nih.gov/pubmed/35255899
http://dx.doi.org/10.1186/s12929-022-00800-7