Cargando…
A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum–infected red blood cell proteome
BACKGROUND: Plasmodium falciparum causes the majority of malaria mortality worldwide, and the disease occurs during the asexual red blood cell (RBC) stage of infection. In the absence of an effective and available vaccine, and with increasing drug resistance, asexual RBC stage parasites are an impor...
Autores principales: | Siddiqui, Ghizal, De Paoli, Amanda, MacRaild, Christopher A, Sexton, Anna E, Boulet, Coralie, Shah, Anup D, Batty, Mitchell B, Schittenhelm, Ralf B, Carvalho, Teresa G, Creek, Darren J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900498/ https://www.ncbi.nlm.nih.gov/pubmed/35254426 http://dx.doi.org/10.1093/gigascience/giac008 |
Ejemplares similares
-
Red Blood Cell BCL-x(L) Is Required for Plasmodium falciparum Survival: Insights into Host-Directed Malaria Therapies
por: Boulet, Coralie, et al.
Publicado: (2022) -
Peroxide Antimalarial Drugs Target Redox Homeostasis
in Plasmodium falciparum Infected Red
Blood Cells
por: Siddiqui, Ghizal, et al.
Publicado: (2022) -
System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion
por: Giannangelo, Carlo, et al.
Publicado: (2020) -
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway
por: Edgar, Rebecca CS, et al.
Publicado: (2022) -
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues
por: Tjhin, Erick T., et al.
Publicado: (2018)