Ciprofloxacin salt and salt co-crystal with di­hydroxy­benzoic acids

The crystal structure of two multi-component crystals of ciprofloxacin [systematic name: 1-cyclo­propyl-6-fluoro-4-oxo-7-(piperazin-1-yl)quinoline-3-carb­­oxy­lic acid], a fluoro­quinolone anti­biotic, namely, ciprofloxacin 2,6-di­hydroxy­benzoate salt, C(17)H(19)FN(3)O(3) (+)·C(7)H(5)O(4) (−), (I), and ciprofloxacin hydro­chloride–3,5-di­hydroxy­benzoic–water (1/1/1), C(17)H(19)FN(3)O(3) (+)·Cl(−)·C(7)H(6)O(4)·H(2)O, (II), were determined. In (I) and (II), the ciprofloxacin cations are connected via head-to-tail N—H⋯O hydrogen bonding. Both structures show an alternating layered arrangement between ciprofloxacin and di­hydroxy­benzoic acid.