Cargando…

Crystal structure and Hirshfeld surface analysis of 2-amino-4-(4-meth­oxy­phen­yl)-6-oxo-1-phenyl-1,4,5,6-tetra­hydro­pyridine-3-carbo­nitrile

The central tetra­hydro­pyridine ring of the title compound, C(19)H(17)N(3)O(2), adopts a screw-boat conformation. In the crystal, strong C—H⋯O and N—H⋯N hydrogen bonds form dimers with R (2) (2)(14) and R (2) (2)(12) ring motifs, respectively, between consecutive mol­ecules along the c-axis directi...

Descripción completa

Detalles Bibliográficos
Autores principales: Asadov, Khammed A., Khrustalev, Victor N., Dobrokhotova, Ekaterina V., Akkurt, Mehmet, Huseynova, Afet T., Akobirshoeva, Anzurat A., Huseynov, Elnur Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900505/
https://www.ncbi.nlm.nih.gov/pubmed/35371539
http://dx.doi.org/10.1107/S205698902200175X
Descripción
Sumario:The central tetra­hydro­pyridine ring of the title compound, C(19)H(17)N(3)O(2), adopts a screw-boat conformation. In the crystal, strong C—H⋯O and N—H⋯N hydrogen bonds form dimers with R (2) (2)(14) and R (2) (2)(12) ring motifs, respectively, between consecutive mol­ecules along the c-axis direction. Inter­molecular N—H⋯O and C—H⋯O hydrogen bonds connect these dimers, forming a three-dimensional network. C—H⋯π inter­actions and π–π stacking inter­actions contribute to the stabilization of the mol­ecular packing. A Hirshfeld surface analysis indicates that the contributions from the most prevalent inter­actions are H⋯H (47.1%), C⋯H/H⋯C (20.9%), O⋯H/H⋯O (15.3%) and N⋯H/H⋯N (11.4%).