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IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in the Absence of the Wiskott–Aldrich Syndrome Protein

Wiskott–Aldrich Syndrome (WAS) is characterized by recurrent infections, thrombocytopenia, and eczema. Here, we show that WASp-deficient mice on a BALB/c background have dysregulated cutaneous immune homeostasis with increased leukocyte accumulation in the skin, 1 week after birth. Increased cutaneo...

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Detalles Bibliográficos
Autores principales: Herman, Katherine E., Yoshida, Takeshi, Hughson, Angela, Grier, Alex, Gill, Steven R., Beck, Lisa A., Fowell, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900519/
https://www.ncbi.nlm.nih.gov/pubmed/35265075
http://dx.doi.org/10.3389/fimmu.2022.817427

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