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Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China

Theileria spp. are a group of parasites primarily transmitted by ticks and can pose a significant threat to domestic and wild animals globally. The main objective of this study was to understand the epidemiology of Theileria spp. in goats of Hainan Island/province, which is the only tropical region...

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Autores principales: Yang, Lu, Wang, Jin-Hua, Upadhyay, Archana, Zhao, Jian-Guo, Huang, Liang-Yuan, Liao, Cheng-Hong, Han, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900600/
https://www.ncbi.nlm.nih.gov/pubmed/35254256
http://dx.doi.org/10.1051/parasite/2022013
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author Yang, Lu
Wang, Jin-Hua
Upadhyay, Archana
Zhao, Jian-Guo
Huang, Liang-Yuan
Liao, Cheng-Hong
Han, Qian
author_facet Yang, Lu
Wang, Jin-Hua
Upadhyay, Archana
Zhao, Jian-Guo
Huang, Liang-Yuan
Liao, Cheng-Hong
Han, Qian
author_sort Yang, Lu
collection PubMed
description Theileria spp. are a group of parasites primarily transmitted by ticks and can pose a significant threat to domestic and wild animals globally. The main objective of this study was to understand the epidemiology of Theileria spp. in goats of Hainan Island/province, which is the only tropical region of China, and to study their hematological profiles in naturally infected goats. A total of 464 blood samples were collected from randomly selected local adult goats (Capra hircus, local domestic breed with black hair), from six cities and eight counties of Hainan, from November 2017 to October 2020. Blood smear microscopy of the sample and a nested polymerase chain reaction (nPCR) targeting the 18S rRNA gene combined with DNA sequencing were used to detect piroplasm infections in goats. Data analysis of the obtained sequences revealed that all the sequences were highly similar to the Theileria luwenshuni 18S rRNA gene sequence from the database. This result is consistent with the microscopic examination. In the hematological test, hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin of the goats naturally infected with T. luwenshuni significantly increased, while mean corpuscular hemoglobin concentration and red blood cell distribution width (RDW) were significantly decreased. Results showed that T. luwenshuni could cause macrocytic, hypochromic anemia in goats. This study provides reliable and comprehensive information about the epidemiology of the parasite infections and hematological profile of the infected goats in Hainan, which encourages further investigations to develop practical control strategies for Theileria spp. infections in tropical areas.
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spelling pubmed-89006002022-03-22 Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China Yang, Lu Wang, Jin-Hua Upadhyay, Archana Zhao, Jian-Guo Huang, Liang-Yuan Liao, Cheng-Hong Han, Qian Parasite Research Article Theileria spp. are a group of parasites primarily transmitted by ticks and can pose a significant threat to domestic and wild animals globally. The main objective of this study was to understand the epidemiology of Theileria spp. in goats of Hainan Island/province, which is the only tropical region of China, and to study their hematological profiles in naturally infected goats. A total of 464 blood samples were collected from randomly selected local adult goats (Capra hircus, local domestic breed with black hair), from six cities and eight counties of Hainan, from November 2017 to October 2020. Blood smear microscopy of the sample and a nested polymerase chain reaction (nPCR) targeting the 18S rRNA gene combined with DNA sequencing were used to detect piroplasm infections in goats. Data analysis of the obtained sequences revealed that all the sequences were highly similar to the Theileria luwenshuni 18S rRNA gene sequence from the database. This result is consistent with the microscopic examination. In the hematological test, hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin of the goats naturally infected with T. luwenshuni significantly increased, while mean corpuscular hemoglobin concentration and red blood cell distribution width (RDW) were significantly decreased. Results showed that T. luwenshuni could cause macrocytic, hypochromic anemia in goats. This study provides reliable and comprehensive information about the epidemiology of the parasite infections and hematological profile of the infected goats in Hainan, which encourages further investigations to develop practical control strategies for Theileria spp. infections in tropical areas. EDP Sciences 2022-03-07 /pmc/articles/PMC8900600/ /pubmed/35254256 http://dx.doi.org/10.1051/parasite/2022013 Text en © L. Yang et al., published by EDP Sciences, 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yang, Lu
Wang, Jin-Hua
Upadhyay, Archana
Zhao, Jian-Guo
Huang, Liang-Yuan
Liao, Cheng-Hong
Han, Qian
Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China
title Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China
title_full Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China
title_fullStr Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China
title_full_unstemmed Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China
title_short Identification of Theileria spp. and investigation of hematological profiles of their infections in goats in Hainan Island, China
title_sort identification of theileria spp. and investigation of hematological profiles of their infections in goats in hainan island, china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900600/
https://www.ncbi.nlm.nih.gov/pubmed/35254256
http://dx.doi.org/10.1051/parasite/2022013
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