Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease

Biliary diseases can cause inflammation, fibrosis, bile duct destruction, and eventually liver failure. There are no curative treatments for biliary disease except for liver transplantation. New therapies are urgently required. We have therefore purified human biliary epithelial cells (hBECs) from h...

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Detalles Bibliográficos
Autores principales: Hallett, John M., Ferreira-Gonzalez, Sofia, Man, Tak Yung, Kilpatrick, Alastair M., Esser, Hannah, Thirlwell, Kayleigh, Macmillan, Mark T., Rodrigo-Torres, Daniel, Dwyer, Benjamin J., Gadd, Victoria L., Ashmore-Harris, Candice, Lu, Wei-Yu, Thomson, John P., Jansen, Maurits A., O’Duibhir, Eoghan, Starkey Lewis, Philip J., Campana, Lara, Aird, Rhona E., Bate, Thomas S.R., Fraser, Alasdair R., Campbell, John D.M., Oniscu, Gabriel C., Hay, David C., Callanan, Anthony, Forbes, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900617/
https://www.ncbi.nlm.nih.gov/pubmed/35245467
http://dx.doi.org/10.1016/j.stem.2022.02.006

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