Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy

Chimeric antigen receptor T cell (CAR T) therapy was a milestone in the treatment of relapsed and refractory B cell malignancies. However, beneficial effects of CAR T cells have not been obtained in solid tumors yet. Herein, we implement a porous microneedle patch that accommodates CAR T cells and a...

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Detalles Bibliográficos
Autores principales: Li, Hongjun, Wang, Zejun, Ogunnaike, Edikan A, Wu, Qing, Chen, Guojun, Hu, Quanyin, Ci, Tianyuan, Chen, Zhaowei, Wang, Jinqiang, Wen, Di, Du, Hongwei, Jiang, Jie, Sun, Jie, Zhang, Xingcai, Dotti, Gianpietro, Gu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RESEARCH ARTICLE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900686/
https://www.ncbi.nlm.nih.gov/pubmed/35265340
http://dx.doi.org/10.1093/nsr/nwab172

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