Fast fragment- and compound-screening pipeline at the Swiss Light Source

Over the last two decades, fragment-based drug discovery (FBDD) has emerged as an effective and efficient method to identify new chemical scaffolds for the development of lead compounds. X-ray crystallography can be used in FBDD as a tool to validate and develop fragments identified as binders by ot...

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Detalles Bibliográficos
Autores principales: Kaminski, Jakub W., Vera, Laura, Stegmann, Dennis P., Vering, Jonatan, Eris, Deniz, Smith, Kate M. L., Huang, Chia-Ying, Meier, Nathalie, Steuber, Julia, Wang, Meitian, Fritz, Günter, Wojdyla, Justyna A., Sharpe, May E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900825/
https://www.ncbi.nlm.nih.gov/pubmed/35234147
http://dx.doi.org/10.1107/S2059798322000705

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