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Enzyme immunoassays (EIA) for serodiagnosis of human leptospirosis: specific IgG3/IgG1 isotyping may further inform diagnosis of acute disease

The laborious microscopic agglutination test (MAT) is the gold standard serologic test for laboratory diagnosis of leptospirosis. We developed EIA based serologic assays using recombinant proteins (rLigA, rLigB, rLipL32) and whole-cell extracts from eight Leptospira serovars as antigen and assessed...

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Detalles Bibliográficos
Autores principales:	Fortes-Gabriel, Elsa, Guedes, Mariana Soares, Shetty, Advait, Gomes, Charles Klazer, Carreira, Teresa, Vieira, Maria Luísa, Esteves, Lisa, Mota-Vieira, Luísa, Gomes-Solecki, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901056/ https://www.ncbi.nlm.nih.gov/pubmed/35196321 http://dx.doi.org/10.1371/journal.pntd.0010241

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