Cargando…
Th1 cells are dispensable for primary clearance of Chlamydia from the female reproductive tract of mice
Protective immune responses to Chlamydia infection within the female reproductive tract (FRT) are incompletely understood. MHC class II-restricted CD4 Th1 responses are believed to be vital for bacterial clearance due to their capacity to secrete IFN-γ, but an essential requirement for T-bet-express...
Autores principales: | Rixon, Jordan A., Depew, Claire E., McSorley, Stephen J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901068/ https://www.ncbi.nlm.nih.gov/pubmed/35196366 http://dx.doi.org/10.1371/journal.ppat.1010333 |
Ejemplares similares
-
Optimal generation of hepatic tissue-resident memory CD4 T cells requires IL-1 and IL-2
por: Depew, Claire E., et al.
Publicado: (2023) -
Gamma Interferon Is Required for Chlamydia Clearance but Is Dispensable for T Cell Homing to the Genital Tract
por: Helble, Jennifer D., et al.
Publicado: (2020) -
B Cells Enhance Antigen-Specific CD4 T Cell Priming and Prevent Bacteria Dissemination following Chlamydia muridarum Genital Tract Infection
por: Li, Lin-Xi, et al.
Publicado: (2013) -
Adhesion Molecules Associated with Female Genital Tract Infection
por: Qualai, Jamal, et al.
Publicado: (2016) -
T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria
por: Pham, Oanh H., et al.
Publicado: (2017)