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Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study

Background: Coronavirus disease 2019 (COVID-19) survivors may continue experiencing diverse symptoms. This study portrays the clinical and laboratory profile of patients with post-acute sequelae of COVID-19’(PASC) at a tertiary care hospital in India.  Methodology: This cross-sectional study enrolle...

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Autores principales: Thyagaraj, Vijayashree, Rao, Akshay, Kulkarni, Ashwin, Shankar, Tharanath, R, Nithin, Unnikrishnan, Hridya, Kalaiah, Keerthi, E, Iniya, Veluswamy, Sundar K, Kumar B S, Nanda, Ravindra, Savita, Shetty, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901080/
https://www.ncbi.nlm.nih.gov/pubmed/35273894
http://dx.doi.org/10.7759/cureus.22888
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author Thyagaraj, Vijayashree
Rao, Akshay
Kulkarni, Ashwin
Shankar, Tharanath
R, Nithin
Unnikrishnan, Hridya
Kalaiah, Keerthi
E, Iniya
Veluswamy, Sundar K
Kumar B S, Nanda
Ravindra, Savita
Shetty, Naresh
author_facet Thyagaraj, Vijayashree
Rao, Akshay
Kulkarni, Ashwin
Shankar, Tharanath
R, Nithin
Unnikrishnan, Hridya
Kalaiah, Keerthi
E, Iniya
Veluswamy, Sundar K
Kumar B S, Nanda
Ravindra, Savita
Shetty, Naresh
author_sort Thyagaraj, Vijayashree
collection PubMed
description Background: Coronavirus disease 2019 (COVID-19) survivors may continue experiencing diverse symptoms. This study portrays the clinical and laboratory profile of patients with post-acute sequelae of COVID-19’(PASC) at a tertiary care hospital in India.  Methodology: This cross-sectional study enrolled patients visiting the post-COVID-19 clinic three weeks after their acute COVID-19 illness. Their clinical, serological, and radiological characteristics were collected and analyzed. Results: Of the 259 participants (age: 48.02±15.27 years; 62.25% men), 168 had PASC manifestations. The most frequently reported symptoms were fatigue (n=71(42.26%)), breathlessness (n=38(22.61%)), and cough (n=35(20.83%)). Patients with PASC had higher body mass index (28.24±5.02 vs. 26.26±3.65; p=0.002), history of hypertension (52 (30.95%) vs. 17 (18.6%); p=0.039), uncontrolled systolic blood pressure (37 (22.03) vs. 14 (15.38); p=0.042), and persistent chest x-ray abnormalities (34 (20.23) vs. 10 (10.98); p=0.048). Conclusion: Fatigue, breathlessness, and cough are common PASC symptoms. Hypertension, obesity, and abnormal chest x-ray findings at follow-up are potential risk factors for developing PASC.
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spelling pubmed-89010802022-03-09 Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study Thyagaraj, Vijayashree Rao, Akshay Kulkarni, Ashwin Shankar, Tharanath R, Nithin Unnikrishnan, Hridya Kalaiah, Keerthi E, Iniya Veluswamy, Sundar K Kumar B S, Nanda Ravindra, Savita Shetty, Naresh Cureus Family/General Practice Background: Coronavirus disease 2019 (COVID-19) survivors may continue experiencing diverse symptoms. This study portrays the clinical and laboratory profile of patients with post-acute sequelae of COVID-19’(PASC) at a tertiary care hospital in India.  Methodology: This cross-sectional study enrolled patients visiting the post-COVID-19 clinic three weeks after their acute COVID-19 illness. Their clinical, serological, and radiological characteristics were collected and analyzed. Results: Of the 259 participants (age: 48.02±15.27 years; 62.25% men), 168 had PASC manifestations. The most frequently reported symptoms were fatigue (n=71(42.26%)), breathlessness (n=38(22.61%)), and cough (n=35(20.83%)). Patients with PASC had higher body mass index (28.24±5.02 vs. 26.26±3.65; p=0.002), history of hypertension (52 (30.95%) vs. 17 (18.6%); p=0.039), uncontrolled systolic blood pressure (37 (22.03) vs. 14 (15.38); p=0.042), and persistent chest x-ray abnormalities (34 (20.23) vs. 10 (10.98); p=0.048). Conclusion: Fatigue, breathlessness, and cough are common PASC symptoms. Hypertension, obesity, and abnormal chest x-ray findings at follow-up are potential risk factors for developing PASC. Cureus 2022-03-06 /pmc/articles/PMC8901080/ /pubmed/35273894 http://dx.doi.org/10.7759/cureus.22888 Text en Copyright © 2022, Thyagaraj et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Thyagaraj, Vijayashree
Rao, Akshay
Kulkarni, Ashwin
Shankar, Tharanath
R, Nithin
Unnikrishnan, Hridya
Kalaiah, Keerthi
E, Iniya
Veluswamy, Sundar K
Kumar B S, Nanda
Ravindra, Savita
Shetty, Naresh
Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
title Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
title_full Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
title_fullStr Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
title_full_unstemmed Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
title_short Clinical and Laboratory Profile of Patients Visiting the Post-COVID-19 Clinic at a Tertiary Care Hospital: A Cross-Sectional Study
title_sort clinical and laboratory profile of patients visiting the post-covid-19 clinic at a tertiary care hospital: a cross-sectional study
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901080/
https://www.ncbi.nlm.nih.gov/pubmed/35273894
http://dx.doi.org/10.7759/cureus.22888
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