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Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters
The application of antiviral coatings to masks and respirators is a potential mitigating step toward reducing viral transmission during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The use of appropriate masks, social distancing, and vaccines is the immediate solution f...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901369/ https://www.ncbi.nlm.nih.gov/pubmed/35284812 http://dx.doi.org/10.1016/j.mtadv.2022.100228 |
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author | Paranthaman, Mariappan Parans Peroutka-Bigus, Nathan Larsen, Kristina R. Phadke, Kruttika S. Summers, Tina Theodore, Merlin Hensley, Dale K. Levine, Alan M. Lee, Richard J. Bellaire, Bryan H. |
author_facet | Paranthaman, Mariappan Parans Peroutka-Bigus, Nathan Larsen, Kristina R. Phadke, Kruttika S. Summers, Tina Theodore, Merlin Hensley, Dale K. Levine, Alan M. Lee, Richard J. Bellaire, Bryan H. |
author_sort | Paranthaman, Mariappan Parans |
collection | PubMed |
description | The application of antiviral coatings to masks and respirators is a potential mitigating step toward reducing viral transmission during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The use of appropriate masks, social distancing, and vaccines is the immediate solution for limiting the viral spread and protecting people from this virus. N95 respirator masks are effective in filtering the virus particles, but they cannot kill or deactivate the virus. We report a possible approach to deactivating SARS-CoV-2 by applying an antimicrobial coating (Goldshield 75) to masks and respirators, rendering them suitable for repeated use. Masks coated with Goldshield 75 demonstrated continuous inactivation of the Alpha and Beta variants of the SARS-CoV-2 over a 3-day period and no loss of inactivation when stored at temperatures at 50 °C. |
format | Online Article Text |
id | pubmed-8901369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-89013692022-03-08 Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters Paranthaman, Mariappan Parans Peroutka-Bigus, Nathan Larsen, Kristina R. Phadke, Kruttika S. Summers, Tina Theodore, Merlin Hensley, Dale K. Levine, Alan M. Lee, Richard J. Bellaire, Bryan H. Mater Today Adv Article The application of antiviral coatings to masks and respirators is a potential mitigating step toward reducing viral transmission during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The use of appropriate masks, social distancing, and vaccines is the immediate solution for limiting the viral spread and protecting people from this virus. N95 respirator masks are effective in filtering the virus particles, but they cannot kill or deactivate the virus. We report a possible approach to deactivating SARS-CoV-2 by applying an antimicrobial coating (Goldshield 75) to masks and respirators, rendering them suitable for repeated use. Masks coated with Goldshield 75 demonstrated continuous inactivation of the Alpha and Beta variants of the SARS-CoV-2 over a 3-day period and no loss of inactivation when stored at temperatures at 50 °C. Elsevier Ltd 2022-06 2022-03-08 /pmc/articles/PMC8901369/ /pubmed/35284812 http://dx.doi.org/10.1016/j.mtadv.2022.100228 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Paranthaman, Mariappan Parans Peroutka-Bigus, Nathan Larsen, Kristina R. Phadke, Kruttika S. Summers, Tina Theodore, Merlin Hensley, Dale K. Levine, Alan M. Lee, Richard J. Bellaire, Bryan H. Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters |
title | Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters |
title_full | Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters |
title_fullStr | Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters |
title_full_unstemmed | Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters |
title_short | Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters |
title_sort | effective antiviral coatings for deactivating sars-cov-2 virus on n95 respirator masks or filters |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901369/ https://www.ncbi.nlm.nih.gov/pubmed/35284812 http://dx.doi.org/10.1016/j.mtadv.2022.100228 |
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