The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States

SARS-CoV-2 was identified and diagnostic methods developed at an impressive speed due in great part to the wider use of molecular methods in 2019 compared with 2002 during the SARS pandemic. The development of rapid and novel molecular diagnostic assays, leveraging of the high adaptability of molecu...

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Autores principales: Dien Bard, Jennifer, Babady, N. Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901381/
https://www.ncbi.nlm.nih.gov/pubmed/35636819
http://dx.doi.org/10.1016/j.cll.2022.02.007
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author Dien Bard, Jennifer
Babady, N. Esther
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Babady, N. Esther
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description SARS-CoV-2 was identified and diagnostic methods developed at an impressive speed due in great part to the wider use of molecular methods in 2019 compared with 2002 during the SARS pandemic. The development of rapid and novel molecular diagnostic assays, leveraging of the high adaptability of molecular tests, and the integration of SARS-CoV-2 genotyping into public health, clinical, and research laboratories have been some of the successes in SARS-CoV-2 molecular testing. The main challenges are related to regulatory hurdles, supply chain constraints, and laboratory preparation.
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spelling pubmed-89013812022-03-08 The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States Dien Bard, Jennifer Babady, N. Esther Clin Lab Med Article SARS-CoV-2 was identified and diagnostic methods developed at an impressive speed due in great part to the wider use of molecular methods in 2019 compared with 2002 during the SARS pandemic. The development of rapid and novel molecular diagnostic assays, leveraging of the high adaptability of molecular tests, and the integration of SARS-CoV-2 genotyping into public health, clinical, and research laboratories have been some of the successes in SARS-CoV-2 molecular testing. The main challenges are related to regulatory hurdles, supply chain constraints, and laboratory preparation. Elsevier Inc. 2022-06 2022-03-08 /pmc/articles/PMC8901381/ /pubmed/35636819 http://dx.doi.org/10.1016/j.cll.2022.02.007 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Dien Bard, Jennifer
Babady, N. Esther
The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States
title The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States
title_full The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States
title_fullStr The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States
title_full_unstemmed The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States
title_short The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States
title_sort successes and challenges of sars-cov-2 molecular testing in the united states
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901381/
https://www.ncbi.nlm.nih.gov/pubmed/35636819
http://dx.doi.org/10.1016/j.cll.2022.02.007
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